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==Carcinogenicity== There is limited evidence that human cancer risk might increase as a result of occupational exposure to large amounts of glyphosate, such as agricultural work, but no good evidence of such a risk from home use, such as in domestic gardening.<ref name=cruk>{{cite web |publisher=Cancer Research UK |title=Food Controversies—Pesticides and organic foods |url=https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/diet-and-cancer/food-controversies#food_controversies4 |date=2016 |archive-url=https://web.archive.org/web/20170206193833/https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/diet-and-cancer/food-controversies#food_controversies4 |access-date=2017-11-28 |archive-date=2017-02-06 }}</ref> The consensus among national pesticide regulatory agencies and scientific organizations is that labeled uses of glyphosate have demonstrated no evidence of human [[carcinogen]]icity.<ref name=Tarazona>{{cite journal |last1=Tarazona |first1=Jose V. |last2=Court-Marques |first2=Daniele |last3=Tiramani |first3=Manuela |last4=Reich |first4=Hermine |last5=Pfeil |first5=Rudolf |last6=Istace |first6=Frederique |last7=Crivellente |first7=Federica |title=Glyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARC |journal=Archives of Toxicology |date=2017-04-03 |volume=91 |issue=8 |pages=2723β2743 |doi=10.1007/s00204-017-1962-5 |pmid=28374158 |pmc=5515989 }}</ref> Organizations such as the Joint [[Food and Agriculture Organization|FAO]]/[[World Health Organization|WHO]] Meeting on Pesticide Residues and the [[European Commission]], Canadian [[Pest Management Regulatory Agency]], and the German [[Federal Institute for Risk Assessment]]<ref>{{Cite web |title = The BfR has finalised its draft report for the re-evaluation of glyphosate - BfR |access-date = 2018-08-18 |url = https://www.bfr.bund.de/en/the_bfr_has_finalised_its_draft_report_for_the_re_evaluation_of_glyphosate-188632.html}}</ref> have concluded that there is no evidence that glyphosate poses a carcinogenic or [[genotoxic]] risk to humans. The final assessment of the [[Australian Pesticides and Veterinary Medicines Authority]] in 2017 was that "glyphosate does not pose a carcinogenic risk to humans".<ref>{{Cite book |publisher=[[SAGE Publishing]] |isbn=978-1-4129-6987-1 |last1=Guston |first1=David |last2=Ludlow |first2=Karinne |title=Encyclopedia of Nanoscience and Society |chapter=Australian Pesticides and Veterinary Medicines Authority |location=[[Thousand Oaks, California|Thousand Oaks, Calif.]] |date=2010 |chapter-url=http://sk.sagepub.com/reference/nanoscience/n22.xml}}</ref> The EPA has evaluated the carcinogenic potential of glyphosate multiple times since 1986. In 1986, glyphosate was initially classified as Group C: "Possible Human Carcinogen", but later recommended as Group D: "Not Classifiable as to Human Carcinogenicity" due to lack of [[statistical significance]] in previously examined rat tumor studies. In 1991, it was classified as Group E: "Evidence of Non-Carcinogenicity for Humans", and in 2015 and 2017, "Not Likely to be Carcinogenic to Humans".<ref>{{Cite web |author=OCSPP |title=EPA Releases Draft Risk Assessments for Glyphosate |work=[[U.S. Environmental Protection Agency|US EPA]] |format=Announcements and Schedules |access-date=August 18, 2018 |date=December 18, 2017 |url=https://www.epa.gov/pesticides/epa-releases-draft-risk-assessments-glyphosate}}</ref><ref>{{cite web |title=Revised Glyphosate Issue Paper: Evaluation of Carcinogenic Potential |url=https://www.regulations.gov/document?D=EPA-HQ-OPP-2009-0361-0073 |publisher=EPA |pages= 12β13 |access-date=September 24, 2019}}</ref> One international scientific organization, the [[International Agency for Research on Cancer]] ([[International Agency for Research on Cancer|IARC]]), classified glyphosate in [[List of IARC Group 2A carcinogens|Group 2A]], "probably carcinogenic to humans" in 2015.<ref name=iarcmono/> The variation in classification between this agency and others has been attributed to "use of different data sets" and "methodological differences in the evaluation of the available evidence".<ref name=Tarazona/> In 2017, California environmental regulators listed glyphosate as βknown to the state to cause cancer.β The state's Office of Environmental Health Hazard Assessment made the decision based in part on the report from the [[International Agency for Research on Cancer|IARC]]. State Proposition 65 requires the state office to add substances the international agency deems carcinogenic in humans or laboratory animals to a state list of cancer-causing items.<ref>{{Cite web |title=How chemicals are added to the Proposition 65 list |url=https://oehha.ca.gov/proposition-65/how-chemicals-are-added-proposition-65-list |access-date=2024-01-21 |website=oehha.ca.gov}}</ref>
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