Editing Rheumatoid arthritis (section)

===Blood===
[[Anemia]] is by far the most common abnormality of the blood cells which can be caused by a variety of mechanisms. The chronic inflammation caused by RA leads to raised [[hepcidin]] levels, leading to [[anemia of chronic disease]] where iron is poorly absorbed and also sequestered into [[macrophages]]. The red cells are of normal size and color (normocytic and Normochromic).<ref>{{cite journal | vauthors = Wilson A, Yu HT, Goodnough LT, Nissenson AR | title = Prevalence and outcomes of anemia in rheumatoid arthritis: a systematic review of the literature | journal = The American Journal of Medicine | volume = 116 | issue = Suppl 7A | pages = 50S–57S | date = April 2004 | pmid = 15050886 | doi = 10.1016/j.amjmed.2003.12.012 }}</ref>

A [[neutropenia|low white blood cell count]] usually only occurs in people with [[Felty's syndrome]] with an enlarged liver and spleen. The mechanism of neutropenia is complex. An [[thrombocytosis|increased platelet count]] occurs when inflammation is uncontrolled.<ref>{{cite journal | vauthors = Tramś E, Malesa K, Pomianowski S, Kamiński R | title = Role of Platelets in Osteoarthritis-Updated Systematic Review and Meta-Analysis on the Role of Platelet-Rich Plasma in Osteoarthritis | journal = Cells | volume = 11 | issue = 7 | pages = 1080 | date = March 2022 | pmid = 35406644 | pmc = 8997794 | doi = 10.3390/cells11071080 | doi-access = free }}</ref>