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=== Labeled versus unlabeled === Both rooted and unrooted trees can be either labeled or unlabeled. A labeled tree has specific values assigned to its leaves, while an unlabeled tree, sometimes called a tree shape, defines a topology only. Some sequence-based trees built from a small genomic locus, such as Phylotree,<ref>{{cite journal |last1=van Oven |first1=Mannis |last2=Kayser |first2=Manfred |title=Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation |journal=Human Mutation |date=2009 |volume=30 |issue=2 |pages=E386βE394 |doi=10.1002/humu.20921 |pmid=18853457 |s2cid=27566749 |ref=phylotree|doi-access=free }}</ref> feature internal nodes labeled with inferred ancestral haplotypes.
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