Editing Mantoux test (section)

==BCG vaccine and the Mantoux test==
The role of Mantoux testing in people who have been vaccinated is disputed.  The US recommends that tuberculin skin testing is not contraindicated for BCG-vaccinated persons, and prior BCG vaccination should not influence the interpretation of the test.  The UK recommends that [[interferon gamma release assay|interferon-γ]] testing should be used to help interpret positive Mantoux tests of over 5&nbsp;mm,<ref>{{Cite web|url=https://www.nice.org.uk/guidance/ng33/chapter/Recommendations#latent-tb|title = Recommendations &#124; Tuberculosis &#124; Guidance &#124; NICE| date=13 January 2016 }}</ref> and repeated tuberculin skin testing must not be done in people who have had BCG vaccinations. In general, the US recommendation may result in a larger number of people being falsely diagnosed with latent tuberculosis, while the UK approach has an increased chance of missing patients with latent tuberculosis who should be treated.{{Citation needed|date=May 2011}}

According to the US guidelines, [[latent tuberculosis]] infection diagnosis and treatment is considered for any BCG-vaccinated person whose skin test is 10&nbsp;mm or greater, if any of these circumstances are present:{{cn|date=May 2024}}
* Was in contact with another person with infectious TB
* Was born or has lived in a high TB prevalence country
* Is continually exposed to populations where TB prevalence is high