Editing Hydrolysis (section)

===DNA===
Hydrolysis of [[DNA]] occurs at a significant rate in vivo.<ref name = Lindahl1993>Lindahl T. Instability and decay of the primary structure of DNA. Nature. 1993 Apr 22;362(6422):709-15. doi: 10.1038/362709a0. PMID 8469282</ref> For example, it is estimated that in each human cell 2,000 to 10,000 DNA [[purine]] bases turn over every day due to hydrolytic depurination, and that this is largely counteracted by specific rapid [[DNA repair]] processes.<ref name = Lindahl1993/> Hydrolytic DNA damages that fail to be accurately repaired may contribute to [[carcinogenesis]] and [[ageing]].<ref name = Lindahl1993/>