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=== Applications === The inclusion of hope in treatment programs has potential in both physical and mental health settings. Hope as a mechanism for improved treatment has been studied in the contexts of PTSD, chronic physical illness, and terminal illness, among other disorders and ailments.<ref name="Phillips 2012">{{cite web|last1=Phillips|first1=Suzanne|title=Does Hope Really Make a Difference? Scientific Findings|url=http://blogs.psychcentral.com/healing-together/2012/07/does-hope-really-make-a-difference-scientific-findings/|website=PsychCentral|access-date=20 April 2015|date=August 2012|archive-date=21 April 2015|archive-url=https://web.archive.org/web/20150421220612/http://blogs.psychcentral.com/healing-together/2012/07/does-hope-really-make-a-difference-scientific-findings/|url-status=dead}}</ref><ref name="Schrank et al. 2008">{{Cite journal|last1=Schrank|first1=Beate|last2=Stanghellini|first2=G|last3=Slade|first3=M|title=Hope in psychiatry: a review of the literature|journal=Acta Psychiatrica Scandinavica|volume=118|issue=6|pages=421β33|doi=10.1111/j.1600-0447.2008.01271.x|pmid=18851720|year=2008|s2cid=205802998|url=https://kclpure.kcl.ac.uk/portal/en/publications/hope-in-psychiatry-a-review-of-the-literature(d22cdded-f92e-4240-9e94-868928a538f6).html|type=Submitted manuscript}}</ref> Within mental health practice, clinicians have suggested using hope interventions as a supplement to more traditional [[Cognitive behavioral therapy|cognitive behavioral therapies]].<ref name="Schrank et al. 2008" /> In terms of support for physical illness, research suggests that hope can encourage the release of [[endorphins]] and [[enkephalin]]s, which help to block pain.<ref name="Enayati 2013">{{cite news|last1=Enayati|first1=Amanda|title=How hope can help you heal|url=http://www.cnn.com/2013/04/11/health/hope-healing-enayati/|website=CNN|access-date=20 April 2015}}</ref>
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