Editing DNA sequencer (section)

===Beckman Coulter===
[[Beckman Coulter]] (now [[Danaher Corporation|Danaher]]) has previously manufactured chain termination and capillary electrophoresis-based DNA sequencers under the model name CEQ, including the CEQ 8000.<ref>{{Cite book |last1=Brown |first1=Ross D. |url=https://books.google.com/books?id=s--zG1BuZSoC&dq=Beckman+Coulter+ceq+8000&pg=PA273 |title=Multiple Myeloma: Methods and Protocols |last2=Ho |first2=P. Joy |date=2008-02-01 |publisher=Springer Science & Business Media |isbn=978-1-59259-916-5 |language=en}}</ref> The company now produces the GeXP Genetic Analysis System, which uses [[dye terminator sequencing]].<ref>{{Cite web|date=August 2014|title=GenomeLab GeXP manual|url=https://scheduleit.mec.cuny.edu/wp-content/uploads/2017/12/GenomeLab-GeXP-manual.pdf|url-status=live|website=[[Medgar Evers College]], [[City University of New York]]|archive-url=https://web.archive.org/web/20211205040329/https://scheduleit.mec.cuny.edu/wp-content/uploads/2017/12/GenomeLab-GeXP-manual.pdf |archive-date=2021-12-05 }}</ref> This method uses a [[thermocycler]] in much the same way as [[Polymerase chain reaction|PCR]] to denature, anneal, and extend DNA fragments, amplifying the sequenced fragments.<ref>{{cite journal|last=Rai|first=Alex J.|author2=Kamath, Rashmi M. |author3=Gerald, William |author4= Fleisher, Martin |title=Analytical validation of the GeXP analyzer and design of a workflow for cancer-biomarker discovery using multiplexed gene-expression profiling|journal=Analytical and Bioanalytical Chemistry|date=29 October 2008|volume=393|issue=5|pages=1505–1511|doi=10.1007/s00216-008-2436-7|pmid=18958454|s2cid=46721686}}</ref><ref>[http://www.beckmancoulter.com/wsrportal/wsr/research-and-discovery/products-and-services/genetic-analysis-systems/genomelab-gexp-genetic-analysis-system/index.htm#overview Beckman Coulter, Inc - GenomeLab GeXP Genetic Analysis System]{{Dead link|date=March 2023}}</ref>