Editing Congenital iodine deficiency syndrome (section)

==Treatment==
Congenital iodine deficiency has been almost eliminated in developed countries through iodine supplementation of food and by [[newborn screening]] using a blood test for thyroid function.<ref name=endocrinopathies>{{Cite journal | last1 = Pass | first1 = K. A. | last2 = Neto | first2 = E. C. | doi = 10.1016/j.ecl.2009.08.005 | title = Update: Newborn Screening for Endocrinopathies | journal = Endocrinology & Metabolism Clinics of North America | volume = 38 | issue = 4 | pages = 827–837 | year = 2009 | pmid = 19944295 }}</ref>

Treatment consists of lifelong administration of [[thyroxine]] (T4). Thyroxine must be dosed as tablets only, even to newborns, as the liquid oral suspensions and compounded forms cannot be depended on for reliable dosing. For infants, the T4 tablets are generally crushed and mixed with breast milk, formula milk or water.  If the medication is mixed with formulas containing iron or soya products, larger doses may be required, as these substances may alter the absorption of thyroid hormone from the gut.<ref name="pmid7596704">{{cite journal |vauthors=Chorazy PA, Himelhoch S, Hopwood NJ, Greger NG, Postellon DC | title = Persistent hypothyroidism in an infant receiving a soy formula: case report and review of the literature | journal = [[Pediatrics (journal)|Pediatrics]] | volume = 96 | issue = 1 Pt 1 | pages = 148–50 |date=July 1995 | pmid = 7596704 }}</ref>  Monitoring TSH blood levels every 2–3 weeks during the first months of life is recommended to ensure that affected infants are at the high end of normal range.<ref>{{Cite journal |last1=Kilberg |first1=Marissa J |last2=Rasooly |first2=Irit R |last3=LaFranchi |first3=Stephen H |last4=Bauer |first4=Andrew J |last5=Hawkes |first5=Colin P |date=2018 |title=Newborn Screening in the United States May Miss Mild Persistent Hypothyroidism |journal=The Journal of Pediatrics |volume=192 |pages=204–208 |doi=10.1016/j.jpeds.2017.09.003 |issn=0022-3476 |pmc=5823276 |pmid=29246344}}</ref>