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==== Sinusoidal ==== [[File:Sinusoid.jpeg|alt=Scanning electron micrograph of a liver sinusoid with fenestrated endothelial cells.|thumb|[[Scanning electron micrograph]] of a [[liver sinusoid]] with fenestrated endothelial cells. Fenestrae are approximately 100 nm in diameter.]] Sinusoidal capillaries or discontinuous capillaries are a special type of open-pore capillary, also known as a ''sinusoid'',<ref name="HLM">{{cite web |title=Histology Laboratory Manual |url= http://www.columbia.edu/itc/hs/medical/sbpm_histology_old/lab/lab07_micrograph.html |website=www.columbia.edu}}</ref> that have wider fenestrations that are 30โ40 [[micrometre]]s (ฮผm) in diameter, with wider openings in the endothelium.<ref name="Saladin">{{Cite book| isbn=9780071222075|title=Human Anatomy|last1=Saladin|first1=Kenneth S.|year=2011|pages=568โ569|publisher=McGraw-Hill }}</ref> Fenestrated capillaries have diaphragms that cover the pores whereas sinusoids lack a diaphragm and just have an open pore. These types of blood vessels allow [[red blood cell|red]] and [[white blood cell]]s (7.5 ฮผm โ 25 ฮผm diameter) and various [[Blood plasma|serum]] proteins to pass, aided by a discontinuous basal lamina. These capillaries lack [[pinocytotic vesicles]], and therefore use gaps present in cell junctions to permit transfer between endothelial cells, and hence across the membrane. Sinusoids are irregular spaces filled with blood and are mainly found in the [[liver]], [[bone marrow]], [[spleen]], and brain [[circumventricular organs]].<ref name="Saladin"/><ref name="gross1">{{cite book|pmid=1410407|year=1992|last1=Gross|first1=P. M|chapter=Chapter 31: Circumventricular organ capillaries |title=Circumventricular Organs and Brain Fluid Environment - Molecular and Functional Aspects|series=Progress in Brain Research|volume=91|pages=219โ33|doi=10.1016/S0079-6123(08)62338-9|isbn=9780444814197}}</ref>
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