Editing Bilirubin (section)

==== Jaundice ====
{{main|Jaundice}}

Hemoglobin acts to transport oxygen which the body receives to all body tissue via blood vessels. Over time, when red blood cells need to be replenished, the hemoglobin is broken down in the spleen; it breaks down into two parts: heme group consisting of iron and bile, and protein fraction. While protein and iron are utilized to renew red blood cells, pigments that make up the red color in blood are deposited into the bile to form bilirubin.<ref>{{cite journal |vauthors=Point WW |date=April 1958 |title=Jaundice |journal=The American Journal of Nursing |volume=58 |issue=4 |pages=556–7 |pmid=13508735}}</ref> Jaundice leads to raised bilirubin levels<ref>[https://kdl.ru/analizy-i-tseny/bilirubin-obshiy Blood testing Bilirubin level] Last full review/revision July 2023 by KDL</ref>  that in turn negatively remove [[elastin]]-rich tissues.<ref>{{cite journal |vauthors=Greenberg DA |date=December 2002 |title=The jaundice of the cell |journal=Proceedings of the National Academy of Sciences of the United States of America |volume=99 |issue=25 |pages=15837–9 |bibcode=2002PNAS...9915837G |doi=10.1073/pnas.012685199 |pmc=138521 |pmid=12461187 |s2cid=30298986 |doi-access=free}}</ref> [[Jaundice]] may be noticeable in the [[sclera]] of the eyes at levels of about 2 to 3&nbsp;mg/dl (34 to 51 μmol/L),<ref>[http://www.merck.com/mmpe/sec03/ch022/ch022d.html Merck Manual Jaundice] Last full review/revision July 2009 by Steven K. Herrine</ref> and in the skin at higher levels.<ref group="note">For conversion, 1&nbsp;mg/dl = 17.1 μmol/L.</ref>

Jaundice is classified, depending upon whether the bilirubin is free or conjugated to [[glucuronic acid]], into conjugated jaundice or unconjugated jaundice.{{Citation needed|date=November 2008}}<!-- not according to [[jaundice]]-->