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=== Visualization === The three most popular ways of visualizing the alpha-helical secondary structure of oligopeptide sequences are (1) a [[helical wheel]],<ref>{{cite journal | vauthors = Schiffer M, Edmundson AB | title = Use of helical wheels to represent the structures of proteins and to identify segments with helical potential | journal = Biophysical Journal | volume = 7 | issue = 2 | pages = 121β135 | date = 1967 | doi = 10.1016/S0006-3495(67)86579-2| pmid = 6048867 | pmc = 1368002 | bibcode = 1967BpJ.....7..121S }}</ref> (2) a wenxiang diagram,<ref>{{cite journal | vauthors = Chou KC, Zhang CT, Maggiora GM | title = Disposition of amphiphilic helices in heteropolar environments | journal = Proteins: Structure, Function, and Genetics | volume = 28 | pages = 99β108 | date = 1997| issue = 1 | doi = 10.1002/(SICI)1097-0134(199705)28:1<99::AID-PROT10>3.0.CO;2-C | pmid = 9144795 | s2cid = 26944184 }}</ref> and (3) a helical net.<ref>{{cite journal | vauthors = Dunnill P | title = The Use of Helical Net-Diagrams to Represent Protein Structures | journal = Biophysical Journal | volume = 8 | issue = 7 | pages = 865β875 | date = 1968 | pmid = 5699810 | pmc = 1367563 | doi = 10.1016/S0006-3495(68)86525-7| bibcode = 1968BpJ.....8..865D }}</ref> Each of these can be visualized with various software packages and web servers. To generate a small number of diagrams, Heliquest<ref>{{cite journal | vauthors = Gautier R, Douguet D, Antonny B, Drin G | title = HELIQUEST: a web server to screen sequences with specific alpha-helical properties | journal = Bioinformatics | volume = 24 | issue = 18 | pages = 2101β2102 | date = 2008 | doi = 10.1093/bioinformatics/btn392| pmid = 18662927 | doi-access = free }}</ref> can be used for helical wheels, and NetWheels<ref>{{cite journal | vauthors = Mol AR, Castro MS, Fontes W | title = NetWheels: A web application to create high quality peptide helical wheel and net projections | journal = bioRxiv | date = 2018 | doi = 10.1101/416347| s2cid = 92137153 }}</ref> can be used for helical wheels and helical nets. To programmatically generate a large number of diagrams, helixvis<ref>{{cite journal | vauthors = Wadhwa RR, Subramanian V, Stevens-Truss R | title = Visualizing alpha-helical peptides in R with helixvis | journal = Journal of Open Source Software | volume = 3 | issue = 31 | pages = 1008 | date = 2018 | doi = 10.21105/joss.01008| bibcode = 2018JOSS....3.1008W | s2cid = 56486576 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Subramanian V, Wadhwa RR, Stevens-Truss R | title = Helixvis: Visualize alpha-helical peptides in Python | journal = ChemRxiv | date = 2020}}</ref> can be used to draw helical wheels and wenxiang diagrams in the R and Python programming languages.
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