Editing Abetalipoproteinemia (section)

== Mechanism ==
Abetalipoproteinemia effects multiple physiological systems, the two most common being the nervous and the skeletal. Disruption of nervous function includes loss of reflexes, speech impairments, tremors or involuntary motor tics, or peripheral neuropathy (damage to the nerves outside of the brain and spinal cord). Peripheral neuropathy causes loss of sensation, weakness or numbness and pain in the extremities through stabbing, burning, or tingling sensations.<ref>{{Cite web |title=Peripheral neuropathy - Symptoms and causes |url=https://www.mayoclinic.org/diseases-conditions/peripheral-neuropathy/symptoms-causes/syc-20352061 |access-date=2019-11-06 |website=Mayo Clinic |language=en}}</ref> Skeletal system developments often include [[lordosis]], [[kyphoscoliosis]], or [[pes cavus]].<ref name="GHR" /> Individuals often have abnormal bleeding due to the difficulty of forming clots.{{Citation needed|date=May 2021}}

Additional complications of the diseases if not properly treated include blindness, mental deterioration, ataxia, loss of peripheral nerve function.<ref>{{Cite web |last=OP |first=Equality Health |date=2023-11-28 |title=The Dangers of Untreated STDs: Consequences and Risks {{!}} Equality Health |url=https://www.ehg.health/the-dangers-of-untreated-stds-consequences-and-risks/ |access-date=2024-12-12 |website=Equality Health Oklahoma |language=en-us}}</ref>