Editing LSD (section)

===Other uses===
In the 1950s and 1960s, some psychiatrists (e.g., [[Oscar Janiger]]) explored the potential effect of LSD on creativity. Experimental studies attempted to measure the effect of LSD on creative activity and aesthetic appreciation.<ref name="PMID6054248"/><ref name="PMID18562421">{{cite journal |vauthors=Sessa B |title=Is it time to revisit the role of psychedelic drugs in enhancing human creativity? |journal=Journal of Psychopharmacology |volume=22 |issue=8 |pages=821–827 |date=November 2008 |pmid=18562421 |s2cid=1908638 |doi=10.1177/0269881108091597}}</ref><ref name="PMID2723891">{{cite journal |vauthors=Janiger O, Dobkin de Rios M |title=LSD and creativity |journal=Journal of Psychoactive Drugs |volume=21 |issue=1 |pages=129–134 |year=1989 |pmid=2723891 |doi=10.1080/02791072.1989.10472150 |url= http://www.erowid.org/culture/characters/janiger_oscar/janiger_oscar.shtml |archive-url=https://web.archive.org/web/20091003005533/http://www.erowid.org/culture/characters/janiger_oscar/janiger_oscar.shtml |archive-date=October 3, 2009 |url-status=live}}</ref><ref name="Stafford-Golightly">{{cite book |title=LSD, the problem-solving psychedelic |vauthors=Stafford PG, Golightly BH |year=1967 |url=http://www.psychedelic-library.org/staf3.htm |url-status=live |archive-url=https://web.archive.org/web/20120417105503/http://www.psychedelic-library.org//staf3.htm |archive-date =April 17, 2012}}</ref> In 1966 Dr. James Fadiman conducted a study with the central question "How can psychedelics be used to facilitate problem solving?" This study attempted to solve 44 different problems and had 40 satisfactory solutions when the FDA banned all research into psychedelics. LSD was a key component of this study.<ref>{{cite web |title=Scientific Problem Solving with Psychedelics – James Fadiman |website=[[YouTube]] |date=May 29, 2013 |url=https://www.youtube.com/watch?v=KtL5fafpRKc |access-date=2023-05-02 |language=en |archive-date=September 8, 2019 |archive-url=https://web.archive.org/web/20190908090741/https://www.youtube.com/watch?v=KtL5fafpRKc |url-status=live }}</ref><ref>{{cite book |vauthors=Fadiman J |title=The psychedelic explorer's guide: safe, therapeutic, and sacred journeys |date=2018 |publisher=Tantor Media |isbn=978-1-9773-7476-9 |oclc=1031461623}}</ref>

Since 2008 there has been ongoing research into using LSD to alleviate anxiety for [[terminally ill]] cancer patients coping with their impending deaths.<ref name=":5" /><ref name="new research"/><ref>{{Cite news |url=http://bazonline.ch/wissen/medizin-und-psychologie/Psychiater-Gasser-bricht-sein-Schweigen/story/25732295|title=Psychiater Gasser bricht sein Schweigen|date=July 28, 2009 |newspaper=Basler Zeitung|access-date=June 19, 2011|archive-url=https://web.archive.org/web/20111006122541/http://bazonline.ch/wissen/medizin-und-psychologie/Psychiater-Gasser-bricht-sein-Schweigen/story/25732295|archive-date=October 6, 2011}}</ref>

A 2012 meta-analysis found evidence that a single dose of LSD in conjunction with various alcoholism treatment programs was associated with a decrease in alcohol abuse, lasting for several months, but no effect was seen at one year. Adverse events included seizure, moderate [[confusion]] and agitation, nausea, [[vomiting]], and acting in a bizarre fashion.<ref name="Lysergic acid diethylamide LSD fo"/>

LSD has been used as a treatment for [[cluster headache]]s with positive results in some small studies.<ref name="PassieHalpernStrichtenoth2008" />

LSD is a potent [[psychoplastogen]], a compound capable of promoting rapid and sustained [[neural plasticity]] that may have wide-ranging therapeutic benefit.<ref name=Ly2018>{{cite journal |title=Psychedelics promote structural and functional neural plasticity |journal=Cell Reports |vauthors=Ly C, Greb AC, Cameron LP, Wong JM, Barragan EV, Wilson PC, Burbach KF, Soltanzadeh Zarandi S, Sood A, Paddy MR, Duim WC, Dennis MY, McAllister AK, Ori-McKenney KM, Gray JA, Olson DE |year=2018 |volume=23 |issue=11 |pages=3170–3182 |doi=10.1016/j.celrep.2018.05.022 |pmid=29898390 |pmc=6082376 }}</ref> LSD has been shown to increase markers of neuroplasticity in human brain [[organoid]]s and improve memory performance in human subjects.<ref>{{Cite news |vauthors=Dolan EW |date=2022-08-11 |title=Neuroscience research suggests LSD might enhance learning and memory by promoting brain plasticity |url=https://www.psypost.org/2022/08/neuroscience-research-suggests-lsd-might-enhance-learning-and-memory-by-promoting-brain-plasticity-63701 |access-date=2022-09-12 |newspaper=Psypost - Psychology News |language=en-US |archive-date=August 26, 2022 |archive-url=https://web.archive.org/web/20220826005449/https://www.psypost.org/2022/08/neuroscience-research-suggests-lsd-might-enhance-learning-and-memory-by-promoting-brain-plasticity-63701 |url-status=live }}</ref>

LSD may have analgesic properties related to pain in terminally ill patients and [[phantom pain]] and may be useful for treating inflammatory diseases including rheumatoid arthritis.<ref name=lsdpain>{{cite journal |vauthors=Whelan A, Johnson MI |title=Lysergic acid diethylamide and psilocybin for the management of patients with persistent pain: a potential role? |journal=Pain Management |volume=8 |issue=3 |pages=217–229 |date=May 2018 |pmid=29722608 |doi=10.2217/pmt-2017-0068 |s2cid=19160293 |url=http://eprints.leedsbeckett.ac.uk/4843/1/LysergicAcidDiethylamide%28LSD%29andPsilocybinAM-JOHNSON.pdf |access-date=August 22, 2020 |archive-date=October 8, 2020 |archive-url=https://web.archive.org/web/20201008201515/http://eprints.leedsbeckett.ac.uk/4843/1/LysergicAcidDiethylamide%28LSD%29andPsilocybinAM-JOHNSON.pdf |url-status=live}}</ref>