Editing Rheumatoid arthritis (section)

===Prognostic factors===
Poor prognostic factors include,
* Persistent synovitis
* Early erosive disease
* Extra-articular findings (including subcutaneous rheumatoid nodules)
* Positive serum RF findings
* Positive serum anti-CCP autoantibodies
* Positive serum 14-3-3η ([[YWHAH]]) levels above 0.5&nbsp;ng/ml <ref name="PMC7299510">{{cite journal | vauthors = Carrier N, Brum-Fernanades AJ, Liang P, Masetto A, Roux S, Biln N, Maksymowych WP, Boire G | title = Impending radiographic erosive progression over the following year in a cohort of consecutive patients with inflammatory polyarthritis: prediction by serum biomarkers | journal = RMD Open | volume = 6 | issue = 1 | pages = e001191 | date = April 2020 | pmid = 32371434 | doi = 10.1136/rmdopen-2020-001191 | pmc = 7299510 }}</ref><ref name="PMC4736641">{{cite journal | vauthors = Carrier N, Marotta A, Brum-Fernanades AJ, Liang P, Masetto A, Menard H, Maksymowcych WP, Boire G | title = Serum levels of 14-3-3η protein supplement C-reactive protein and rheumatoid arthritis-associated antibodies to predict clinical and radiographic outcomes in a prospective cohort of patients with recent-onset inflammatory polyarthritis | journal = Arthritis Research & Therapy | volume = 18 | issue = 37 | date = Feb 2016 | page = 37 | pmid = 26832367 | doi = 10.1186/s13075-016-0935-z | doi-broken-date = 1 November 2024 | pmc = 4736641 | doi-access = free }}</ref>
* Carriership of HLA-DR4 "Shared Epitope" alleles
* Family history of RA
* Poor functional status
* Socioeconomic factors<ref name=":16" />
* Elevated acute phase response (erythrocyte sedimentation rate [ESR], C-reactive protein [CRP])
* Increased clinical severity.
* Distance from primary care and specialist care in rural communities<ref name=":16" />