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==Prevention== Primary prevention can be accomplished by the reduction of modifiable risk factors that increase the likelihood of developing urethritis. These factors include, but are not limited to, sexual intercourse (particularly unprotected intercourse) and genital irritation from contact with tight clothing, physical activity, and various irritants such as soap, lotion and [[spermicides]].<ref name="Young_2020" /> Bacterial infections leading to gonococcal and non-gonococcal urethritis can be prevented by: * [[sexual abstinence]] * use of barrier contraception, such as [[condom]]s * pre-exposure vaccination: [[HPV vaccine|HPV]] and [[Hepatitis B vaccine]]s * reducing number of sexual partners<ref>{{cite web|date=2020-07-21|title=Clinical Prevention Guidance - 2015 STD Treatment Guidelines|url=https://www.cdc.gov/std/tg2015/clinical.htm|access-date=2020-07-31|website=www.cdc.gov|language=en-us}}</ref> [[Chlorhexidine]] is an antibacterial agent that covers a wide spectrum of gram-positive and gram-negative bacteria. Rinsing with 15 ml of a 0.12% or 10 ml of 0.2% [[chlorhexidine]] solution for 30 seconds produced large and prolonged reductions in salivary bacterial counts within 7 hours of its use. One hypothesis in 2010 posed the potential use of [[chlorhexidine]] rinsing before oral sex as a prevention strategy of recurrent non-gonococcal urethritis caused by bacteria entering the urethra from oral cavity following "insertive oral intercourse", particularly in men.<ref>{{cite journal | vauthors = Kolahi J, Abrishami M, Fazilati M, Soolari A | title = Chlorhexidine rinse for prevention of urethritis in AMAB individuals linked to oral sex | journal = International Archives of Medicine | volume = 3 | issue = 1 | pages = 9 | date = June 2010 | pmid = 20540731 | pmc = 2892434 | doi = 10.1186/1755-7682-3-9 | doi-access = free }}</ref> However, actual clinical studies are yet to be carried out in order to prove this hypothesis.
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