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===Women and children=== According to the 2015 Cochrane systematic review, atorvastatin showed greater cholesterol-lowering effect in women than in men compared to rosuvastatin.<ref name="AdamsTsangWright2015">{{cite journal |vauthors=Adams SP, Tsang M, Wright JM |date=March 2015 |title=Lipid-lowering efficacy of atorvastatin |journal=The Cochrane Database of Systematic Reviews |volume=2015 |issue=3 |pages=CD008226 |doi=10.1002/14651858.CD008226.pub3 |pmc=6464917 |pmid=25760954}}</ref> In children, statins are effective at reducing cholesterol levels in those with [[familial hypercholesterolemia]].<ref name=":0">{{cite journal | vauthors = Vuorio A, Kuoppala J, Kovanen PT, Humphries SE, Tonstad S, Wiegman A, Drogari E, Ramaswami U | title = Statins for children with familial hypercholesterolemia | journal = The Cochrane Database of Systematic Reviews | volume = 2019 | issue = 11 | date = November 2019 | pmid = 31696945 | pmc = 6836374 | doi = 10.1002/14651858.CD006401.pub5 }}</ref> Their long term safety is, however, unclear.<ref name=":0" /><ref>{{cite journal | vauthors = Lamaida N, Capuano E, Pinto L, Capuano E, Capuano R, Capuano V | title = The safety of statins in children | journal = Acta Paediatrica | volume = 102 | issue = 9 | pages = 857β862 | date = September 2013 | pmid = 23631461 | doi = 10.1111/apa.12280 | s2cid = 22846175 }}</ref> Some recommend that if lifestyle changes are not enough statins should be started at 8 years old.<ref>{{cite journal | vauthors = Braamskamp MJ, Wijburg FA, Wiegman A | title = Drug therapy of hypercholesterolaemia in children and adolescents | journal = Drugs | volume = 72 | issue = 6 | pages = 759β772 | date = April 2012 | pmid = 22512364 | doi = 10.2165/11632810-000000000-00000 | s2cid = 21141894 }}</ref>
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