Editing Sarin (section)

===Toxicity===
As a nerve gas, sarin in its purest form is estimated to be 26 times more deadly than [[cyanide]].<ref>{{cite web |title=Sarin gas as chemical agent – ThinkQuest- Library |url=http://library.thinkquest.org/27393/dreamwvr/agents/sarin1.htm |access-date=August 13, 2007 |url-status=dead |archive-url=https://web.archive.org/web/20070808094319/http://library.thinkquest.org/27393/dreamwvr/agents/sarin1.htm |archive-date=August 8, 2007}}</ref> The [[median lethal dose|LD<sub>50</sub>]] of [[subcutaneous injection|subcutaneously injected]] sarin in mice is 172 μg/kg.<ref>{{cite journal |last=Inns |first=RH |author2=NJ Tuckwell |author3=JE Bright |author4=TC Marrs |title=Histochemical Demonstration of Calcium Accumulation in Muscle Fibres after Experimental Organophosphate Poisoning |journal=Hum Exp Toxicol |date=July 1990 |volume=9 |issue=4 |pages=245–250 |pmid=2390321 |bibcode=1990HETox...9..245I |s2cid=20713579 |doi=10.1177/096032719000900407}}</ref>

Sarin is highly toxic, whether by contact with the skin or breathed in. The toxicity of sarin in humans is largely based on calculations from studies with animals. The lethal concentration of sarin in air is approximately 28–35&nbsp;mg per cubic meter per minute for a two-minute exposure time by a healthy adult breathing normally (exchanging 15 liters of air per minute, lower 28 mg/m<sup>3</sup> value is for general population).<ref>{{cite book |title=Chemical Warfare Agents: Biomedical and Psychological Effects, Medical Countermeasures, and Emergency Response |last1=Lukey |first1=Brian J. |last2=Romano |first2=James A. Jr. |last3=Salem |first3=Harry |date=April 11, 2019 |publisher=CRC Press |isbn=978-0-429-63296-9 |language=en |url=https://books.google.com/books?id=DQqWDwAAQBAJ&q=exponent+lethality+vx&pg=PA174}}</ref> This number represents the estimated lethal concentration for 50% of exposed victims, the [[median lethal dose#Conventions|LCt<sub>50</sub>]] value. The [[median lethal dose#Conventions|LCt<sub>95</sub>]] or [[median lethal dose#Conventions|LCt<sub>100</sub>]] value is estimated to be 40–83 mg per cubic meter for exposure time of two minutes.<ref>{{cite book |title=Review of Acute Human-Toxicity Estimates for GB (Sarin) |last=Toxicology |first=National Research Council (US) Committee on |date=1997 |publisher=National Academies Press (US) |language=en |url=https://www.ncbi.nlm.nih.gov/books/NBK233733/}}</ref><ref>{{cite journal |last1=Bide |first1=R. W. |last2=Armour |first2=S. J. |last3=Yee |first3=E. |date=2005 |title=GB toxicity reassessed using newer techniques for estimation of human toxicity from animal inhalation toxicity data: new method for estimating acute human toxicity (GB) |journal=Journal of Applied Toxicology |volume=25 |issue=5 |pages=393–409 |issn=0260-437X |pmid=16092087 |s2cid=8769521 |doi=10.1002/jat.1074}}</ref> Calculating effects for different exposure times and concentrations requires following specific toxic load models. In general, brief exposures to higher concentrations are more lethal than comparable long time exposures to low concentrations.<ref>{{cite book |title=Chemical Warfare Agents: Biomedical and Psychological Effects, Medical Countermeasures, and Emergency Response |last1=Lukey |first1=Brian J. |last2=Romano |first2=James A. Jr. |last3=Salem |first3=Harry |date=April 11, 2019 |publisher=CRC Press |isbn=978-0-429-63296-9 |language=en |url=https://books.google.com/books?id=DQqWDwAAQBAJ&q=exponent+lethality+vx&pg=PA171}}</ref> There are many ways to make relative comparisons between toxic substances. The list below compares sarin to some current and historic chemical warfare agents, with a direct comparison to the respiratory LCt<sub>50</sub>:

* [[Hydrogen cyanide]], 2,860&nbsp;mg/(min·m<sup>3</sup>)<ref name=":0">{{cite book |title=US Army Field Manual 3–11.9 Potential Military Chemical/Biological Agents and Compounds |publisher=United States Department of Defense |year=2005}}</ref> – Sarin is 81 times more lethal
* [[Phosgene]], 1,500&nbsp;mg/(min·m<sup>3</sup>)<ref name=":0"/> – Sarin is 43 times more lethal
* [[Sulfur mustard]], 1,000&nbsp;mg/(min·m<sup>3</sup>)<ref name=":0"/> – Sarin is 28 times more lethal
* [[Chlorine]], 19,000&nbsp;mg/(min·m<sup>3</sup>)<ref>{{cite book |title=US Army Field Manual 3–9 Potential Military Chemical/Biological Agents and Compounds |publisher=United States Department of Defense |year=1990 |pages=71}}</ref> – Sarin is 543 times more lethal