Editing Salicylic acid (section)

==Safety==
{{main|Salicylate poisoning}}
If high concentrations of salicylic ointment are used [[topical medication|topically]], high levels of salicylic acid can enter the blood. In such cases , [[hemodialysis]] would be required to avoid further complications.<ref>{{cite journal | vauthors = Péc J, Strmenová M, Palencárová E, Pullmann R, Funiaková S, Visnovský P, Buchanec J, Lazarová Z | title = Salicylate intoxication after use of topical salicylic acid ointment by a patient with psoriasis | journal = Cutis | volume = 50 | issue = 4 | pages = 307–309 | date = October 1992 | pmid = 1424799 }}</ref>

Cosmetic applications of the drug pose no significant risk.<ref name="labib">{{cite journal|vauthors=Labib R, Bury D, Boisleve F, Eichenbaum G, Girard S, Naciff J, Leal M, Wong J |title=A kinetic-based safety assessment of consumer exposure to salicylic acid from cosmetic products demonstrates no evidence of a health risk from developmental toxicity |journal=Regulatory Toxicology and Pharmacology|volume=94 |issue= |pages=245–251 |date=April 2018 |pmid=29410076 |doi=10.1016/j.yrtph.2018.01.026 |s2cid=46877699 |doi-access=free }}</ref> Even in a worst-case use scenario in which one was using multiple salicylic acid-containing topical products, the aggregate plasma concentration of salicylic acid was well below what was permissible for acetylsalicylic acid [[Aspirin|(aspirin).]]<ref name=labib/> Since oral aspirin (which produces much higher salicylic acid plasma concentrations than dermal salicylic acid applications) poses no significant adverse pregnancy outcomes in terms of frequency of stillbirth, birth defects or developmental delay, use of salicylic acid containing cosmetics is safe for pregnant women.<ref name=labib/> Salicylic acid is present in most fruits and vegetables as for example in greatest quantities in [[Berry|berries]] and in beverages like tea.