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===Low-flow priapism=== Causes of low-flow priapism include [[sickle cell anemia]] (most common in children), [[leukemia]], and other blood dyscrasias such as [[thalassemia]] and [[multiple myeloma]], and the use of various drugs, as well as cancers.<ref name="FernandesSouza2018"/> A genome-wide association study on Brazilian patients with sickle cell disease identified four single nucleotide polymorphisms in LINC02537 and [[NAALADL2]] significantly associated with priapism.<ref>{{Cite journal |doi=10.1016/j.jsxm.2019.09.012 |pmc=6904926 |pmid=31668730|title=Clinical and Genetic Predictors of Priapism in Sickle Cell Disease: Results from the Recipient Epidemiology and Donor Evaluation Study III Brazil Cohort Study |year=2019 |last1=Cintho Ozahata |first1=Mina |last2=Page |first2=Grier P. |last3=Guo |first3=Yuelong |last4=Ferreira |first4=João Eduardo |last5=Dinardo |first5=Carla Luana |last6=Carneiro-Proietti |first6=Anna Bárbara F. |last7=Loureiro |first7=Paula |last8=Mota |first8=Rosimere Afonso |last9=Rodrigues |first9=Daniela O.W. |last10=Belisario |first10=André Rolim |last11=Maximo |first11=Claudia |last12=Flor-Park |first12=Miriam V. |last13=Custer |first13=Brian |last14=Kelly |first14=Shannon |last15=Sabino |first15=Ester Cerdeira |author16=International Component of the NHLBI Recipient Epidemiology Donor Evaluation Study (REDS-III) |journal=The Journal of Sexual Medicine |volume=16 |issue=12 |pages=1988–1999 }}</ref> Other conditions that can cause priapism include [[Fabry's disease]], as well as [[neurology|neurologic disorders]] such as [[spinal cord]] lesions and spinal cord trauma (priapism has been reported in people who have been hanged; see [[death erection]]). Priapism can also be caused by reactions to [[medication]]s. The most common medications that cause priapism are intra-cavernous injections for the treatment of [[erectile dysfunction]] ([[papaverine]], [[alprostadil]]). Other medication groups reported are [[antihypertensives]] (e.g. [[Doxazosin]]), [[antipsychotic]]s (e.g., [[chlorpromazine]], [[clozapine]]), [[antidepressant]]s (most notably [[trazodone]]), [[anti-convulsant]] and [[mood stabilizer]] drugs such as [[sodium valproate]].<ref>{{cite journal |vauthors=Bansal S, Gupta SK | title = Sodium Valproate induced priapism in an adult with bipolar affective disorder | journal = [[Indian Journal of Pharmacology]] | volume = 45 | issue = 6 | pages = 629–30 |date=November 2013 | doi = 10.4103/0253-7613.121383| pmc = 3847259 | pmid=24347777 | doi-access = free }}</ref> [[Anticoagulants]], [[cantharides]] (''Spanish Fly'') and recreational drugs ([[alcohol (drug)|alcohol]], [[heroin]] and [[cocaine]]) have been associated. Priapism is also known to occur from bites of the [[Brazilian wandering spider]].<ref>{{cite web|url=http://www.webmd.com/erectile-dysfunction/news/20090924/spider-venom-for-erectile-dysfunction|title=Spider Venom for Erectile Dysfunction?|work=webmd.com|access-date=11 February 2015|url-status=live|archive-url=https://web.archive.org/web/20150211214317/http://www.webmd.com/erectile-dysfunction/news/20090924/spider-venom-for-erectile-dysfunction|archive-date=11 February 2015}}</ref>
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