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===Variation=== The size of the pancreas varies considerably.{{sfn|Gray's|2016|pp=1179β1189}} Several [[anatomical variation]]s exist, relating to the embryological development of the two [[pancreatic bud]]s. The pancreas develops from these buds on either side of the duodenum. The [[pancreatic bud|ventral bud]] rotates to lie next to the [[pancreatic bud|dorsal bud]], eventually fusing. In about 10% of adults, an [[accessory pancreatic duct]] may be present if the main duct of the dorsal bud of the pancreas does not regress; this duct opens into the [[minor duodenal papilla]].<ref name=Langmans2019 /> If the two buds themselves, each having a duct, do not fuse, a pancreas may exist with two separate ducts, a condition known as a [[pancreas divisum]]. This condition has no physiologic consequence.<ref name="KanthMedscape">{{EMedicine|article|185307|Pancreatic Divisum}}</ref> If the ventral bud does not fully rotate, an [[annular pancreas]] may exist, where part or all of the duodenum is encircled by the pancreas. This may be associated with [[duodenal atresia]].<ref name="Noh2012">{{cite journal |last1=Noh |first1=TH |last2=Lee |first2=SE |last3=Park |first3=JM |title=Laparoscopic treatment of annular pancreas in adults: report of a case. |journal=Korean Journal of Hepato-biliary-pancreatic Surgery |date=February 2012 |volume=16 |issue=1 |pages=43β5 |doi=10.14701/kjhbps.2012.16.1.43 |pmid=26388905|pmc=4575014 }}</ref>
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