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==Sequences== {{main|Nucleic acid sequence}} {{further|Genetics}} One DNA or RNA molecule differs from another primarily in the [[nucleic acid sequence|sequence of nucleotides]]. Nucleotide sequences are of great importance in biology since they carry the ultimate instructions that encode all biological molecules, molecular assemblies, subcellular and cellular structures, organs, and organisms, and directly enable cognition, memory, and behavior. Enormous efforts have gone into the development of experimental methods to determine the nucleotide sequence of biological DNA and RNA molecules,<ref>Gilbert, Walter G. 1980. DNA Sequencing and Gene Structure (Nobel Lecture) http://nobelprize.org/nobel_prizes/chemistry/laureates/1980/gilbert-lecture.html</ref><ref>Sanger, Frederick. 1980. Determination of Nucleotide Sequences in DNA (Nobel Lecture) http://nobelprize.org/nobel_prizes/chemistry/laureates/1980/sanger-lecture.html</ref> and today hundreds of millions of nucleotides are [[DNA sequencing|sequenced]] daily at genome centers and smaller laboratories worldwide. In addition to maintaining the GenBank nucleic acid sequence database, the [[National Center for Biotechnology Information]] (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI web site.<ref>{{cite journal | title = Database resources of the National Center for Biotechnology Information | journal = Nucleic Acids Research | volume = 42 | issue = Database issue | pages = D7-17 | date = January 2014 | pmid = 24259429 | pmc = 3965057 | doi = 10.1093/nar/gkt1146 | author1 = NCBI Resource Coordinators }}</ref>
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