Editing Norwegian Forest Cat (section)

==Health==
In an experiment directed by John C. Fyfea, Rebeccah L. Kurzhals, and others, it was concluded that a complex rearrangement in the breed's [[Glycogen branching enzyme]] (GBE1) can cause both a perinatal hypoglycemic collapse and a late-juvenile-onset neuromuscular degeneration in [[glycogen storage disease type IV]] in the breed.<ref>{{Cite journal | last1 = Fyfe | first1 = J. C. | last2 = Kurzhals | first2 = R. L. | last3 = Hawkins | first3 = M. G. | last4 = Wang | first4 = P. | last5 = Yuhki | first5 = N. | last6 = Giger | first6 = U. | last7 = Van Winkle | first7 = T. J. | last8 = Haskins | first8 = M. E. | last9 = Patterson | first9 = D. F. | doi = 10.1016/j.ymgme.2006.12.003 | last10 = Henthorn | first10 = P. S. | title = A complex rearrangement in GBE1 causes both perinatal hypoglycemic collapse and late-juvenile-onset neuromuscular degeneration in glycogen storage disease type IV of Norwegian forest cats | journal = Molecular Genetics and Metabolism | volume = 90 | issue = 4 | pages = 383–392 | year = 2007 | pmid =  17257876| pmc =2063609 |quote=Deficiency of glycogen branching enzyme (GBE) activity causes glycogen storage disease type IV (GSD IV), an autosomal recessive error of metabolism. Abnormal glycogen accumulates in myocytes, hepatocytes, and neurons, causing variably progressive, benign to lethal organ dysfunctions. A naturally occurring orthologue of human GSD IV was described previously in Norwegian Forest cats (NFC).}}</ref><ref>{{cite book|title=Cat Owner's Home Veterinary Handbook, Fully Revised and Updated|publisher=[[John Wiley & Sons|Howell Book House]]|isbn=978-0-470-09530-0|author1=Eldredge, Debra |author2=Carlson, Delbert DVM |author3=Carlson, Liisa |author4=Griffin, James |edition=3rd|page=403|date=10 December 2007}}</ref> This disorder, while rare, can prove fatal to cats that have it.<ref name=ASPCA/> Glycogen storage disease type IV due to branching enzyme deficiency was found in an inbred family of Norwegian Forest Cats.<ref>{{Cite journal|last1=Fyfe|first1=John C.|last2=Giger|first2=Urs|last3=Van Winkle|first3=Thomas J.|last4=Haskins|first4=Mark E.|last5=Steinberg|first5=Sheldon A.|last6=Wang|first6=Ping|last7=Patterson|first7=Donald F.|date=December 1992|title=Glycogen Storage Disease Type IV: Inherited Deficiency of Branching Enzyme Activity in Cats|journal=Pediatric Research|language=en|volume=32|issue=6|pages=719–725|doi=10.1203/00006450-199212000-00020|pmid=1337588|issn=1530-0447|doi-access=free}}</ref> 

The breed has also been known to suffer from [[Hip dysplasia#Other animals|hip dysplasia]],<ref>{{cite book|last=Eldredge|first=Debra|title=Pills For Pets: The A to Z Guide to Drugs and Medications for Your Animal Companion|year=2003|publisher=[[Kensington Books|Citadel Press]]|isbn=978-0-8065-2436-8|page=[https://archive.org/details/pillsforpetsthet0000eldr/page/63 63]|chapter=17: Preventative Health Care for Your Pet|quote=An example here is the Norwegian Forest Cat. Dedicated owners learned that their cats have the possibility of suffering from hip dysplasia.|chapter-url=https://archive.org/details/pillsforpetsthet0000eldr/page/63}}</ref> which is a rare, partially hereditary disease of the hip joint.<ref>{{cite book|title=What Your Cat Is Trying To Tell You|year=2000|publisher=[[St. Martin's Press]]|isbn=978-0-312-97288-2|author1=Simon, John|author2=Pederson, Stephanie|edition=1st|page=[https://archive.org/details/whatyourcatistry00simo/page/168 168]|type=Mass Market Paperback|url=https://archive.org/details/whatyourcatistry00simo/page/168}}</ref>

An analysis of pedigree records of cats in England found evidence of hereditary [[cardiomyopathy]].<ref>{{Cite journal|last1=März|first1=Imke|last2=Wilkie|first2=Lois J|last3=Harrington|first3=Norelene|last4=Payne|first4=Jessie R|last5=Muzzi|first5=Ruthnea A L|last6=Häggström|first6=Jens|last7=Smith|first7=Ken|last8=Luis Fuentes|first8=Virginia|date=30 October 2014|title=Familial cardiomyopathy in Norwegian Forest cats|journal=Journal of Feline Medicine and Surgery|language=en-US|volume=17|issue=8|pages=681–691|doi=10.1177/1098612x14553686|pmid=25359788|pmc=11104058 |s2cid=28958322|issn=1098-612X|url=https://researchonline.rvc.ac.uk/id/eprint/8726/1/8726.pdf }}</ref> A 2005 study looking at 17 cases of [[Eosinophilic granuloma|eosinophilic granuloma complex]] in Norwegian Forest Cats found a link between the cats after reviewing pedigree analysis, suggesting a hereditary nature of the condition.<ref>{{Cite journal|last1=Leistra|first1=W. H. G.|last2=Oost|first2=B. A. van|last3=Willemse|first3=T.|date=30 April 2005|title=Non-pruritic granuloma in Norwegian forest cats|url=https://veterinaryrecord.bmj.com/content/156/18/575|journal=Veterinary Record|language=en|volume=156|issue=18|pages=575–577|doi=10.1136/vr.156.18.575|issn=0042-4900|pmid=15866902|s2cid=1377327|access-date=9 March 2020|archive-date=19 March 2020|archive-url=https://web.archive.org/web/20200319181408/https://veterinaryrecord.bmj.com/content/156/18/575|url-status=dead}}</ref>