Editing Mitochondrion (section)

====Cristae====
[[File:MitochondrionCAM.jpg|thumb|250 px|right|Cross-sectional image of cristae in a [[rat]] liver mitochondrion to demonstrate the likely 3D structure and relationship to the inner membrane]]
{{Main|Crista}}

The inner mitochondrial membrane is compartmentalized into numerous folds called [[crista]]e, which expand the surface area of the inner mitochondrial membrane, enhancing its ability to produce ATP. For typical liver mitochondria, the area of the inner membrane is about five times as large as that of the outer membrane. This ratio is variable and mitochondria from cells that have a greater demand for ATP, such as muscle cells, contain even more cristae. Mitochondria within the same cell can have substantially different crista-density, with the ones that are required to produce more energy having much more crista-membrane surface.<ref name="Cserép-2018">{{cite journal | vauthors = Cserép C, Pósfai B, Schwarcz AD, Dénes Á | title = Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites | journal = eNeuro | volume = 5 | issue = 1 | pages = ENEURO.0390–17.2018 | date = 2018 | pmid = 29383328 | pmc = 5788698 | doi = 10.1523/ENEURO.0390-17.2018 }}</ref> These folds are studded with small round bodies known as [[F-ATPase|F{{sub|1}} particles]] or oxysomes.<ref name="Mannella-2006">{{cite journal | vauthors = Mannella CA | title = Structure and dynamics of the mitochondrial inner membrane cristae | journal = Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | volume = 1763 | issue = 5–6 | pages = 542–548 | year = 2006 | pmid = 16730811 | doi = 10.1016/j.bbamcr.2006.04.006 | doi-access =  }}</ref>