Editing Melrose Place (section)

===Main cast members===
* [[Josie Bissett]] as [[Jane Mancini|Jane Andrews Mancini]] (seasons 1–5, 7), fashion designer, originally from Chicago, married to Michael Mancini, later involved with Sam Towler, Robert Wilson, Chris Marchette, Richard Hart, Jake Hanson and Kyle McBride
* [[Thomas Calabro]] as [[Michael Mancini|Dr. Michael Mancini]], resident then cardiology surgeon at Wilshire Memorial Hospital, originally from [[New Jersey]], married to Jane, and later marries Sydney Andrews, Kimberly Shaw and Megan Lewis, also involved with Amanda Woodward, Brandi Carson, Taylor McBride and Lexi Sterling
* [[Amy Locane]] as [[List of Melrose Place characters#Sandy Harling|Sandy Harling]] (season 1), aspiring actress and waitress at the bar Shooters, originally from [[South Carolina]], involved with Jake
* [[Doug Savant]] as [[Matt Fielding]] (seasons 1–6), openly gay social worker and physician at Wilshire Memorial, [[Green card marriage|marries]] Katya Petrova, involved with Jeffrey Lindley, Dr. Paul Graham, Alan Ross and Dan Hathaway
* [[Grant Show]] as [[Jake Hanson (Beverly Hills, 90210)|Jake Hanson]] (seasons 1–5), mechanic and carpenter, owner of Jake's Bikes and later Shooters, involved with Colleen Patterson, Perry Morgan, [[Kelly Taylor]], Sandy Harling, Jo Reynolds, Amanda, Sydney, Shelley Hanson and Jane, later marries Alison Parker
* [[Andrew Shue]] as [[List of Melrose Place characters#Billy Campbell|Billy Campbell]] (seasons 1–7), taxi driver, later writer at Escapade Magazine, then copywriter for D&D Advertising, engaged to Alison Parker and later marries Brooke Armstrong and Samantha Reilly, also involved with Amanda, Susan Madsen and Jennifer Mancini
* [[Courtney Thorne-Smith]] as [[List of Melrose Place characters#Alison Parker|Alison Parker Armstrong Hanson]] (seasons 1–5), advertising executive at D&D Advertising and later waitress at Shooters, originally from [[Wisconsin]], involved with Keith Gray, Steve McMillan, Zack Phillips and Terry Parsons, engaged to Billy and later marries Hayley Armstrong and Jake Hanson
* [[Vanessa Estelle Williams|Vanessa Williams]] as [[List of Melrose Place characters#Rhonda Blair|Rhonda Blair]] (season 1), aerobics instructor, engaged to Terrence Haggard
* [[Daphne Zuniga]] as [[Jo Reynolds]] (seasons 1–4), freelance photographer, originally from New York City, previously married to Charles Reynolds, involved with Jake Hanson, Steve McMillan, Reed Carter, Jess Hansen, Richard Hart and Dr. Dominick O'Malley
* [[Heather Locklear]] as [[Amanda Woodward (Melrose Place)|Amanda Woodward Parezi Burns McBride Blake]] (seasons 2–7, recurring season 1), vice-president then president at D&D Advertising and Amanda Woodward Advertising, owner of the Melrose Place complex, previously married to Jack Parezi and later marries Dr. Peter Burns, Kyle McBride and Rory Blake, also involved with Billy, Jake, Michael, Bobby Parezi and Craig Field
* [[Laura Leighton]] as [[Sydney Andrews|Sydney Andrews Mancini Field]] (seasons 3–5, recurring season 1–2), Jane's younger sister, waitress at Shooters, then prostitute, stripper and receptionist at Burns & Mancini, marries Michael and Craig, also involved with Jake, Chris Marchette, Bobby Parezi, Kyle McBride and Carter Gallavan
* [[Marcia Cross]] as [[Kimberly Shaw|Dr. Kimberly Shaw Mancini]] (seasons 4–5, recurring season 1–3), resident doctor at Wilshire Memorial, originally from [[Cleveland]], marries Michael, also involved with Peter and Dr. Brett Cooper
* [[Kristin Davis]] as [[List of Melrose Place characters#Brooke Armstrong|Brooke Armstrong Campbell]] (season 4, recurring season 3), employee at D&D Advertising, marries Billy
* [[Jack Wagner (actor)|Jack Wagner]] as [[List of Melrose Place characters#Peter Burns|Dr. Peter Howell Burns]] (seasons 4–7, recurring season 3), chief of staff at Wilshire Memorial, originally from [[Texas]], previously married to Beth Davis and later Amanda and Eve Cleary, also involved with Caitlin Mills, Alycia Barnett, Kimberly, Taylor and Lexi
* [[Rob Estes]] as [[List of Melrose Place characters#Kyle McBride|Kyle McBride]] (seasons 5–7), chef and restaurant owner, former marine, originally from [[Boston]], married to Taylor and later Amanda, also involved with Christine Denton, Jennifer, Sydney and Jane
* [[Brooke Langton]] as [[List of Melrose Place characters#Samantha Reilly|Samantha Reilly Campbell]] (seasons 5–7, recurring season 4), artist and salesperson at Jane's (later Sydney's), originally from [[Crisfield, Maryland|Maryland]], marries Billy, also involved with Craig and Jeff Baylor
* [[Lisa Rinna]] as [[List of Melrose Place characters#Taylor McBride|Victoria Taylor Davis McBride]] (seasons 5–7), restaurant co-owner, originally from [[Boston]], married to Kyle, also involved with Peter, Michael and Nick Reardon
* [[Kelly Rutherford]] as [[List of Melrose Place characters#Megan Lewis|Megan Lewis Mancini McBride]] (seasons 5–7), prostitute, later receptionist at Burns, Mancini & Cooper and Amanda Woodward Advertising, marries Michael and Ryan McBride, also involved with Coop
* [[David Charvet]] as [[List of Melrose Place characters#Craig Field|Craig Field]] (seasons 5–6), son of the chairman of D&D Advertising, marries Sydney, also involved with Amanda and Jennifer
* [[Linden Ashby]] as [[List of Melrose Place characters#Brett Cooper|Dr. Brett "Coop" Cooper]] (seasons 6–7), surgeon and partner at Burns, Mancini & Cooper, originally from [[Cleveland]], married to Lexi, also involved with Kimberly and Megan
* [[Alyssa Milano]] as [[List of Melrose Place characters#Jennifer Mancini|Jennifer Mancini]] (seasons 6–7, recurring season 5), Michael's younger sister, originally from [[New Jersey]], bartender at Upstairs, involved with Kyle, Craig and Billy
* [[Jamie Luner]] as [[List of Melrose Place characters#Lexi Sterling|Lexi Sterling Cooper]] (seasons 6–7), interior designer, later owner of Sterling Conway Enterprises, married to Coop, also involved with Peter, Ryan and Michael
* [[John Haymes Newton]] as [[List of Melrose Place characters#Ryan McBride|Ryan McBride]] (season 7), Kyle's younger brother, executive at Amanda Woodward Advertising, married to Callie McBride and later Megan, also involved with Lexi