Editing Lymph node (section)

=== Cells ===
In the lymphatic system a lymph node is a [[Lymphatic system#Structure|secondary lymphoid organ]].<ref name="Grays2016" /> Lymph nodes contain [[lymphocyte]]s, a type of [[white blood cell]], and are primarily made up of [[B cell]]s and [[T cells]].<ref name="Grays2016" /> B cells are mainly found in the outer cortex where they are clustered together as [[follicular B cell]]s in lymphoid follicles, and T cells and [[dendritic cells]] are mainly found in the ''paracortex''.{{sfn|Davidson's|2018|p=67}}

There are fewer cells in the medulla than the cortex.<ref name="Grays2016" /> The medulla contains plasma cells, as well as [[macrophage]]s which are present within the medullary sinuses.{{sfn|Davidson's|2018|p=67}}

As part of the reticular network, there are [[follicular dendritic cells]] in the B cell follicle and [[fibroblastic]] [[reticular cell]]s in the T cell cortex. The reticular network provides structural support and a surface for adhesion of the dendritic cells, macrophages and lymphocytes. It also allows exchange of material with blood through the [[high endothelial venules]] and provides the growth and regulatory factors necessary for activation and maturation of immune cells.<ref name=kaldjian>{{cite journal | vauthors = Kaldjian EP, Gretz JE, Anderson AO, Shi Y, Shaw S | title = Spatial and molecular organization of lymph node T cell cortex: a labyrinthine cavity bounded by an epithelium-like monolayer of fibroblastic reticular cells anchored to basement membrane-like extracellular matrix | journal = International Immunology | volume = 13 | issue = 10 | pages = 1243–53 | date = October 2001 | pmid = 11581169 | doi = 10.1093/intimm/13.10.1243 | doi-access = free }}</ref>