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===Exploration=== [[File:Mars500.jpg|thumb|upright=1.2|A 3D plan of the Russia-based [[MARS-500]] complex, used for conducting ground-based experiments that complement ISS-based preparations for a [[human mission to Mars]]]] The ISS provides a location in the relative safety of low Earth orbit to test spacecraft systems that will be required for long-duration missions to the Moon and Mars. This provides experience in operations, maintenance, and repair and replacement activities on-orbit. This will help develop essential skills in operating spacecraft farther from Earth, reduce mission risks, and advance the capabilities of interplanetary spacecraft.<ref name="ResProg">{{cite web|title=ISS Research Program|url=http://spaceflightsystems.grc.nasa.gov/Advanced/ISSResearch/|url-status=dead|archive-url=https://web.archive.org/web/20090213140014/http://spaceflightsystems.grc.nasa.gov/Advanced/ISSResearch/|archive-date=13 February 2009|access-date=27 February 2009|publisher=NASA}}</ref> Referring to the [[MARS-500]] experiment, a crew isolation experiment conducted on Earth, ESA states, "Whereas the ISS is essential for answering questions concerning the possible impact of weightlessness, radiation and other space-specific factors, aspects such as the effect of long-term isolation and confinement can be more appropriately addressed via ground-based simulations".<ref name="esa mars500">{{Cite web|url=https://www.esa.int/Science_Exploration/Human_and_Robotic_Exploration/Mars500/Mars500_study_overview|title=Mars500: study overview|date=4 June 2011|publisher=[[European Space Agency]]|url-status=live|archive-url=https://web.archive.org/web/20230819135747/https://www.esa.int/Science_Exploration/Human_and_Robotic_Exploration/Mars500/Mars500_study_overview|archive-date=19 August 2023}}</ref> Sergey Krasnov, the head of human space flight programmes for Russia's space agency, Roscosmos, in 2011 suggested a "shorter version" of MARS-500 may be carried out on the ISS.<!--there are better refs for this including the mention of 2014β2015 I think --><ref name="Mars thing on ISS">{{cite web|date=4 November 2011|title=Space station may be site for next mock Mars mission|url=https://www.newscientist.com/blogs/shortsharpscience/2011/11/space-station-may-be-site-for.html|website=New Scientist|access-date=1 September 2017|archive-date=11 July 2017|archive-url=https://web.archive.org/web/20170711030614/https://www.newscientist.com/blogs/shortsharpscience/2011/11/space-station-may-be-site-for.html|url-status=dead}}</ref> In 2009, noting the value of the partnership framework itself, Sergey Krasnov wrote, "When compared with partners acting separately, partners developing complementary abilities and resources could give us much more assurance of the success and safety of space exploration. The ISS is helping further advance near-Earth space exploration and realisation of prospective programmes of research and exploration of the Solar system, including the Moon and Mars."<ref name="IAF2009">{{cite web|title=The Sustainable Utilisation of the ISS Beyond 2015|url=http://www.iafastro.org/docs/2009/ISS2015.pdf|url-status=dead|archive-url=https://web.archive.org/web/20120426051318/http://www.iafastro.org/docs/2009/ISS2015.pdf|archive-date=26 April 2012|access-date=15 December 2011|publisher=International Astronautical Congress}}</ref> [[Human mission to Mars|A crewed mission to Mars]] may be a multinational effort involving space agencies and countries outside the current ISS partnership. In 2010, ESA Director-General Jean-Jacques Dordain stated his agency was ready to propose to the other four partners that China, India, and South Korea be invited to join the ISS partnership.<ref name="ESAproposesInvite">{{Cite news|last=de Selding|first=Peter B.|date=3 February 2010|title=ESA Chief Lauds Renewed U.S. Commitment to Space Station, Earth Science|work=Space News|url=http://spacenews.com/esa-chief-lauds-renewed-us-commitment-space-station-earth-science/}}</ref> NASA chief [[Charles Bolden]] stated in February 2011, "Any mission to Mars is likely to be a global effort."<ref name="Mars a global effort">{{Cite news|url=https://www.space.com/11335-nasa-mars-exploration-space-station.html|title=Space Station Crucial for Going to Mars, NASA Chief Says|last=Chow|first=Denise|date=8 April 2011|url-status=live|archive-url=https://web.archive.org/web/20230811162758/https://www.space.com/11335-nasa-mars-exploration-space-station.html|archive-date=11 August 2023|work=[[Space.com]]}}</ref> Currently, [[Wolf Amendment|US federal legislation]] prevents NASA co-operation with China on space projects without approval by the [[FBI]] and Congress.<ref name="justice1">{{cite web|last=Seitz|first=Virginia A.|title=Memorandum Opinion for the General Counsel, Office of Science and Technology Policy|date=19 September 2011|url=https://www.justice.gov/olc/2011/conduct-diplomacy.pdf|website=justice.gov|publisher=[[United States Department of Justice|US Justice Department]]|archive-url=https://web.archive.org/web/20120713080223/http://www.justice.gov/olc/2011/conduct-diplomacy.pdf|access-date=23 May 2012|archive-date=13 July 2012|url-status=dead|page=3}}</ref>
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