Editing Electrophysiology (section)

===Optical electrophysiological techniques===

Optical electrophysiological techniques were created by scientists and engineers to overcome one of the main limitations of classical techniques. Classical techniques allow observation of electrical activity at approximately a single point within a volume of tissue. Classical techniques singularize a distributed phenomenon.  Interest in the spatial distribution of bioelectric activity prompted development of molecules capable of emitting light in response to their electrical or chemical environment.  Examples are [[voltage sensitive dye]]s and fluorescing proteins.
After introducing one or more such compounds into tissue via perfusion, injection or gene expression, the 1 or 2-dimensional distribution of electrical activity may be observed and recorded.{{cn|date=August 2024}}