Editing Ehlers–Danlos syndrome (section)

===Brittle-cornea syndrome===
Brittle-cornea syndrome (BCS) is characterized by the progressive thinning of the [[cornea]], early-onset progressive [[keratoglobus]] or keratoconus, nearsightedness, hearing loss, and blue [[sclera]]e.<ref name=GARD2017/><ref name="GARD_2019">{{cite web|url=https://rarediseases.info.nih.gov/diseases/1019/brittle-cornea-syndrome|title=Brittle cornea syndrome | work = Genetic and Rare Diseases Information Center (GARD) – an NCATS Program | publisher = U.S. National Institutes of Health  |access-date=2019-06-03}}</ref> Classic symptoms, such as hypermobile joints and hyperelastic skin, are also seen often.<ref>{{cite web|url=https://www.omim.org/entry/614170|title=OMIM Entry – # 614170 – Brittle Cornea Syndrome 2; BCS2|website=www.omim.org|access-date=2018-06-18}}</ref> It has two types. Type 1 occurs due to variations in the ''[[ZNF469]]'' gene. Type 2 is due to variations in the ''PRDM5'' gene.<ref name="GARD_2019"/>