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===Metatropic dysplasia=== Metatropic means "changing form" and refers to this form of skeletal dysplasia as there is an abnormality in the growth plates.<ref>{{cite web |url=https://www.hopkinsmedicine.org/health/conditions-and-diseases/metatropic-dysplasia#:~:text=What%20is%20metatropic%20dysplasia%3F,flattening%20of%20the%20vertebral%20bodies |title=Metatropic Dysplasia | |publisher=Johns Hopkins Medicine |date=2022-02-03 |access-date=2022-03-02}}</ref> Skeletal changes continue over time and may need surgical intervention to help protect the lungs.<ref name="NIH Rared Dseases">{{cite web|url=https://rarediseases.info.nih.gov/diseases/3571/metatropic-dysplasia |title=Metatropic dysplasia | Genetic and Rare Diseases Information Center (GARD) β an NCATS Program |website=Rarediseases.info.nih.gov |date= |access-date=2022-03-02}}</ref> Symptoms starting at birth may be mild or can be fatal.<ref name="Medlineplus.gov">{{Cite web|url=https://medlineplus.gov/genetics/condition/metatropic-dysplasia/|title=Metatropic dysplasia: MedlinePlus Genetics|website=Medlineplus.gov|access-date=2 March 2022}}</ref> There are recognizable features in individuals with this genetic disorder. Some are short stature, narrow chest, "facial features such as a prominent forehead, underdevelopment of the upper jaw, cheekbones and eye sockets (midface hypoplasia), and a squared-off jaw."<ref name="NIH Rared Dseases"/> It is considered a more severe skeletal dysplasia, but is very rare, with the exact number of those affected unknown.<ref name="Medlineplus.gov"/> Prognosis is largely on a case-by-case basis depending on the severity, and life expectancy may not be impacted unless there are respiratory complications.<ref>{{cite web|url=https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2635 |title=Orphanet: Metatropic dysplasia |website=Orpha.net |date=2017-05-17 |access-date=2022-03-02}}</ref>
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