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=== Adverse effects and potential uses=== The use of clove for any medicinal purpose has not been approved by the US [[Food and Drug Administration]], and its use may cause [[adverse event|adverse effects]] if taken orally by people with [[liver disease]], [[blood clotting]] and [[immune system]] disorders, or [[food allergy|food allergies]].<ref name=drugs/> Cloves are used in [[traditional medicine]] as an [[Oil of cloves|essential oil]], which is intended to be an [[anodyne]] ([[analgesic]]) mainly for dental emergencies.<ref>Balch, Phyllis and Balch, James. ''Prescription for Nutritional Healing'', 3rd ed., Avery Publishing, 2000, p. 94</ref> There is evidence that clove oil containing [[eugenol]] is effective for [[toothache]] pain and other types of pain.<ref name="drugs">{{cite web |title=Clove |url=https://www.drugs.com/mtm/clove.html |publisher=Drugs.com |access-date=25 December 2024 |date=22 February 2024}}</ref><ref name="nih">{{cite web |url=https://www.nlm.nih.gov/medlineplus/druginfo/natural/251.html|title=Clove|publisher=MedlinePlus, U.S. National Library of Medicine and National Institutes of Health |date=28 March 2024 |access-date=25 December 2024}}</ref><ref>{{Cite web |title=Eugenol - COLCORONA Clinical Trial |url=https://www.colcorona.net/de/haarausfall-nach-corona |access-date=2022-12-12 |website=www.colcorona.net}}</ref> Clove essential oil may prevent the growth of ''[[Enterococcus faecalis]]'' bacteria which may be present in an unsuccessful [[root canal]] treatment.<ref>{{Cite journal |date=2022 |title=Effectiveness of Mixed Clove Flower Extract (Syzygium Aromaticum) And Sweet Wood (Cinnamon Burmanni) on the Growth of Enterococcus Faecalis |url=https://medicopublication.com/index.php/ijfmt/article/view/17639 |journal=Indian Journal of Forensic Medicine & Toxicology |volume=16 |issue=1 |doi=10.37506/ijfmt.v16i1.17639|s2cid=245045753 |doi-access=free |last1=Sarahfin Aslan |last2=Masriadi |last3=Nur Rahmah Hasanuddin |last4=Andi Tenri Biba Mallombasang |last5=Nur Azizah a.r |pages=1089–1094 }}</ref> One review reported the efficacy of eugenol combined with [[zinc oxide]] as an [[analgesia|analgesic]] for [[alveolar osteitis]].<ref>{{cite journal |pmc=4598935 |year=2015 |last1=Taberner-Vallverdú |first1=M. |title=Efficacy of different methods used for dry socket management: A systematic review |journal=Medicina Oral Patología Oral y Cirugia Bucal |volume=20 |issue=5 |pages=e633–e639 |last2=Nazir |first2=M. |last3=Sanchez-Garces |first3=M. Á. |last4=Gay-Escoda |first4=C. |doi=10.4317/medoral.20589 |pmid=26116842}}</ref> Studies to determine its effectiveness for fever reduction, as a [[mosquito]] repellent, and to prevent [[premature ejaculation]] have been inconclusive.<ref name=drugs/><ref name=nih/> It remains unproven whether [[blood sugar]] levels are reduced by cloves or clove oil.<ref name=nih/> The essential oil may be used in [[aromatherapy]].<ref name="drugs" />
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