Editing Autolysin (section)

== Families ==

=== LytC amidase family ===

==== LytC ====
LytC as well as LytD are considered as two major autolysins that contribute to vegetative cell wall growth and account for 95% of the autolytic activity in B. subtilis. LytC is found in the cell wall. LytB, a non-autolysin, was found to enhance LytC activity.<ref name=":1" /> LytC and LytA interact and function together for lysis and cell death.<ref>{{cite journal | vauthors = García P, Paz González M, García E, García JL, López R | title = The molecular characterization of the first autolytic lysozyme of Streptococcus pneumoniae reveals evolutionary mobile domains | journal = Molecular Microbiology | volume = 33 | issue = 1 | pages = 128–138 | date = July 1999 | pmid = 10411730 | doi = 10.1046/j.1365-2958.1999.01455.x | doi-access = free }}</ref>{{Infobox enzyme
| Name = Gametolysin
| EC_number = 3.4.24.38
| CAS_number = 97089-74-2
| IUBMB_EC_number = 3/4/24/38
| GO_code = 
| image = 
| width = 
| caption =
}}

==== CwlC ====
CwlC is found in the mother cell wall and functions for the lysis of the mother cell wall.<ref name=":1" /> CwlC does not have a signal sequence but participates in late sporulation and is present in the cell wall.<ref name=":2">{{cite journal | vauthors = Kuroda A, Asami Y, Sekiguchi J | title = Molecular cloning of a sporulation-specific cell wall hydrolase gene of Bacillus subtilis | journal = Journal of Bacteriology | volume = 175 | issue = 19 | pages = 6260–6268 | date = October 1993 | pmid = 8407798 | pmc = 206722 | doi = 10.1128/jb.175.19.6260-6268.1993 }}</ref><ref>{{cite journal | vauthors = Smith TJ, Foster SJ | title = Characterization of the involvement of two compensatory autolysins in mother cell lysis during sporulation of Bacillus subtilis 168 | journal = Journal of Bacteriology | volume = 177 | issue = 13 | pages = 3855–3862 | date = July 1995 | pmid = 7601853 | pmc = 177106 | doi = 10.1128/jb.177.13.3855-3862.1995 }}</ref> It was found in B. subtilis that CwlC is able to hydrolyze both vegetative cell walls and spore peptidoglycan.<ref name=":2" />

=== LytD glucosaminidase family ===
This family of autolysin consist of only LytD itself. LytD functions for vegetative growth. Autolytic activity is found within the C-terminal region with catalytic domain homologous to the glucosaminidase domain. LytD is found in the cell wall. LytD activity was studied in B. subtilis and glucosaminidase activity was found in mature glycan strands due to the presence of MurNAc at the nonreducing ends.<ref name=":1" />