Editing Anticoagulant (section)

===Coumarins (vitamin K antagonists)===<!--this section heading is linked to from [[Warfarin]]-->
{{Further|Vitamin K antagonist}}
These oral anticoagulants are derived from [[coumarin]] found in many plants. A prominent member of this class, [[warfarin]] (Coumadin), was found to be the anticoagulant most prescribed in a large multispecialty practice.<ref>{{Cite journal |vauthors=Efird LE, Chasler J, Alexander GC, McGuire M |date=Jun 21, 2016 |title=Prescribing Patterns of Novel Anticoagulants Within a Statewide Multispecialty Practice |url=https://www.pharmacytimes.com/view/prescribing-patterns-of-novel-anticoagulants-within-a-statewide-multispecialty-practice |journal=American Journal of Pharmacy Benefits |volume=8 |issue=3 |pages=97–102}}</ref> The anticoagulant effect takes at least 48 to 72 hours to develop. Where an immediate effect is required, [[heparin]] is given concomitantly. These anticoagulants are used to treat patients with [[deep-vein thrombosis]] (DVT) and [[pulmonary embolism]] (PE) and to prevent emboli in patients with [[atrial fibrillation]] (AF), and mechanical [[prosthetic heart valve]]s. Other examples are [[acenocoumarol]], [[phenprocoumon]], [[atromentin]], and [[phenindione]].{{citation needed|date=November 2021}}

The coumarins [[brodifacoum]] and [[difenacoum]] are used as mammalicides (particularly as [[rodenticide]]s) but are not used medically.{{citation needed|date=August 2022}}