Editing Aflatoxin (section)

=== In other animals ===
In dogs, aflatoxin has potential to lead to liver disease. Low levels of aflatoxin exposure require continuous consumption for several weeks to months in order for signs of liver dysfunction to appear.<ref name=bingham/> Some articles have suggested the toxic level in dog food is 100–300&nbsp;ppb and requires continuous exposure or consumption for a few weeks to months to develop aflatoxicosis.<ref name=bastianello/> No information is available to suggest that recovered dogs will later succumb to an aflatoxin-induced disease.

Turkeys are extremely susceptible to aflatoxicosis. Recent studies have revealed that this is due to the efficient [[cytochrome P450]] mediated metabolism of aflatoxin B<sub>1</sub> in the liver of turkeys and deficient [[glutathione-S-transferase]] mediated detoxification.<ref name=rawal1/><ref name=rawal2/>

Some studies on pregnant hamsters showed a significant relationship between exposure of aflatoxin B<sub>1</sub> (4&nbsp;mg/kg, single dose) and the appearance of [[teratology|developmental anomalies]] in their offspring.<ref name=goldblatt/>

In 2005, Diamond Pet Foods discovered aflatoxin in a product manufactured at their facility in [[Gaston, South Carolina]].<ref>[https://www.fda.gov/AboutFDA/CentersOffices/ORA/ORAElectronicReadingRoom/ucm061767.htm FDA Inspection Report-Diamond Gaston SC Plant 12/21/2005-1/19/2006].</ref><ref>[https://www.fda.gov/Safety/Recalls/ArchiveRecalls/2005/ucm111929.htm 2005 Recall], FDA</ref> In 23 states, Diamond voluntarily recalled 19 products formulated with corn and manufactured in the Gaston facility. Testing of more than 2,700 finished product samples conducted by laboratories confirmed that only two date codes of two adult dog formulas had the potential to be toxic.<ref>AKC Standard Article Contaminated Diamond Pet Food Products and 'Best By' Dates Narrowed {{usurped|1=[https://web.archive.org/web/20110707101136/http://www.akcstandard.com/article/contaminated-dog-food-1-06.html/ Akcstandard.com]}}</ref>

In December 2020 and January 2021, Midwestern Pet Foods recalled dog food that contained fatal levels of aflatoxin.<ref>{{Cite journal|last=Medicine|first=Center for Veterinary|date=2021-01-12|title=FDA Alert: Certain Lots of Sportmix Pet Food Recalled for Potentially Fatal Levels of Aflatoxin|url=https://www.fda.gov/animal-veterinary/outbreaks-and-advisories/fda-alert-certain-lots-sportmix-pet-food-recalled-potentially-fatal-levels-aflatoxin|journal=FDA|language=en}}</ref> As many as 70 dogs had died from aflatoxin poisoning by January 12, 2021.<ref>{{Cite web|last=Tyko|first=Kelly|title=Dog food recall expands: More than 70 dogs have died and 80 pets sick after eating Sportsmix pet food|url=https://www.usatoday.com/story/money/shopping/2021/01/12/recall-alert-midwestern-pet-foods-sportsmix-recalled-aflatoxin-risk/6642035002/|access-date=2021-01-13|website=USA TODAY|language=en-US}}</ref>
[[File:41598_2018_35246_Fig1_HTML.png|thumb|Schematic summarizing the major AFB1 and AFM1 contamination/exposure routes and adverse health effects to human]]