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=== Alzheimer's disease === Based on studies, it is evident that obesity has a strong association with vascular and metabolic disease which could potentially be linked to Alzheimer's disease. Recent studies have also shown an association between mid-life obesity and dementia, but the relationship between later life obesity and dementia is less clear.<ref name="Razay2006">{{cite journal | vauthors = Razay G, Vreugdenhil A, Wilcock G | title = Obesity, abdominal obesity and Alzheimer disease | journal = Dementia and Geriatric Cognitive Disorders | volume = 22 | issue = 2 | pages = 173β6 | year = 2006 | pmid = 16847377 | doi = 10.1159/000094586 | s2cid = 24351283 }}</ref> A study by Debette et al. (2010) examining over 700 adults found evidence to suggest higher volumes of visceral fat, regardless of overall weight, were associated with smaller brain volumes and increased risk of [[dementia]].<ref>{{cite journal | vauthors = Debette S, [[Alexa Beiser|Beiser A]], Hoffmann U, Decarli C, O'Donnell CJ, Massaro JM, Au R, Himali JJ, Wolf PA, Fox CS, Seshadri S | display-authors = 6 | title = Visceral fat is associated with lower brain volume in healthy middle-aged adults | journal = Annals of Neurology | volume = 68 | issue = 2 | pages = 136β44 | date = August 2010 | pmid = 20695006 | pmc = 2933649 | doi = 10.1002/ana.22062 }}</ref><ref>{{cite news |url=http://news.bbc.co.uk/2/hi/health/8693947.stm |publisher=BBC News |title='Beer belly' link to Alzheimer's |date=2010-05-20 }}</ref><ref>{{cite web | vauthors = Mitchell S |url=http://www.nbcnews.com/id/23800703 |archive-url=https://web.archive.org/web/20150318143512/http://www.nbcnews.com/id/23800703/ |url-status=dead |archive-date=18 March 2015 |title=Bulging belly now could mean dementia later |publisher=NBC News |date=2008-03-26 |access-date=2013-01-05}}</ref> Alzheimer's disease and abdominal obesity has a strong correlation and with metabolic factors added in, the risk of developing Alzheimer's disease was even higher. Based on logistic regression analyses, it was found that obesity was associated with an almost 10-fold increase risk of Alzheimer's disease.<ref name="Razay2006" />
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