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==== Seleucid Empire ==== * [[Antiochus II Theos|Antiochus II]] leaves [[Berenice (Seleucid queen)|Berenice]] in order to live again with his former wife [[Laodice I|Laodice]] and his son [[Seleucus II Callinicus|Seleucus]]. However, Laodice poisons him and proclaims her son as King Seleucus II Callinicus, while her supporters in [[Antioch]] kill Berenice and her children who have taken refuge at Daphne, near Antioch, in [[Syria]]. * Berenice's brother, [[Ptolemy III Euergetes|Ptolemy III]], sets about to avenge his sister's murder by invading Syria which begins the [[Third Syrian War]] (also known as the [[Laodicean War]]). Ptolemy III's navy, perhaps with the aid of rebels in the cities, advances against Seleucus II's forces as far as [[Thrace]], across the [[Hellespont]], and also captures some islands off the [[Anatolia]]n coast. * Ptolemy III wins major victories over Seleucus II in Syria and Anatolia and briefly occupies Antioch. These victories are marred by the loss of the [[Cyclades]] to [[Antigonus II Gonatas]] in the [[Battle of Andros (246 BC)|Battle of Andros]]. * Seleucus II Callinicus' mother, Laodice attempts to take control over the Seleucid Empire by insisting that Seleucus II make his younger brother, [[Antiochus Hierax]], co-regent and give him all the Seleucid territory in [[Anatolia]]. Antiochus promptly declares independence and begins fighting a war with his brother. * In order to secure the [[Bactria]]n King [[Diodotus I|Diodotus']] friendship, Seleucus II Callinicus arranges the marriage of one of his sisters to King Diodotus.
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