Editing Α-Ketoglutaric acid (section)

====Formation of the neurotransmitter gamma-aminobutyric acid====
A study conducted on the [[GABAergic]] [[neurons]] (i.e., nerve cells) in the [[neocortex]] of rat brains reported that the [[cytosol]]ic form of the [[aspartate transaminase]] enzyme metabolizes α-ketoglutarate to [[glutamate]] which in turn is metabolized by [[glutamic acid decarboxylase]] to the [[Neurotransmitter#Modulation|inhibitory neurotransmitter]] [[gamma-aminobutyric acid]]. These metabolic reactions occur at the ends of the inhibitory [[axons]] of the GABAergic neurons and result in the release of gamma-aminobutyric acid which then inhibits the activation of nearby neurons.<ref name="pmid7838383"/><ref name="pmid32002773">{{cite journal | vauthors = Robinson MB, Lee ML, DaSilva S | title = Glutamate Transporters and Mitochondria: Signaling, Co-compartmentalization, Functional Coupling, and Future Directions | journal = Neurochemical Research | volume = 45 | issue = 3 | pages = 526–540 | date = March 2020 | pmid = 32002773 | pmc = 7060825 | doi = 10.1007/s11064-020-02974-8 | url = }}</ref>