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===Pregnancy=== More than 75% of women with rheumatoid arthritis have symptoms improve during pregnancy but might have symptoms worsen after delivery.<ref name="McGraw Hill"/> [[Methotrexate]] and [[leflunomide]] are teratogenic (harmful to foetus) and not used in pregnancy. It is recommended women of childbearing age should use contraceptives to avoid pregnancy and to discontinue its use if pregnancy is planned.<ref name="Wasserman" /><ref name="chapter94" /> Low dose of [[prednisolone]], [[hydroxychloroquine]] and [[sulfasalazine]] are considered safe in pregnant women with rheumatoid arthritis. Prednisolone should be used with caution as the side effects include infections and fractures.<ref>{{cite journal | vauthors = Gotzsche PC, Johansen HK | title = Short-term low-dose corticosteroids vs placebo and nonsteroidal antiinflammatory drugs in rheumatoid arthritis | journal = The Cochrane Database of Systematic Reviews | issue = 3 | pages = CD000189 | date = 2005-01-24 | volume = 2005 | pmid = 15266426 | doi = 10.1002/14651858.cd000189.pub2 | pmc = 7043293 }}</ref>
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