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====1800s==== * '''1800:''' [[Alessandro Volta]] invents the [[voltaic pile]], an early form of [[Battery (electricity)|battery]] in [[Italy]], based on previous works by [[Luigi Galvani]]. * '''1802:''' [[Humphry Davy]] invents the [[arc lamp]] (exact date unclear; not practical as a light source until the invention of efficient electric generators).<ref>{{cite web |url=http://archives.theiet.org/about/Arclamps/arclamps.htm |title=The Arc Lamp |access-date=29 April 2011 |url-status=dead |archive-url=https://web.archive.org/web/20110207170412/http://archives.theiet.org/about/Arclamps/arclamps.htm |archive-date=7 February 2011}}</ref> * '''1804:''' [[Friedrich Sertürner]] discovers [[morphine]] as the first active alkaloid extracted from the opium poppy plant.<ref>{{cite book|url=https://books.google.com/books?id=MtOiLVWBn8cC&pg=PA20|page=20|title=Molecular, clinical and environmental toxicology|author=Andreas Luch|publisher=Springer|year=2009|isbn=978-3-7643-8335-0}}</ref> * '''1804:''' [[Joseph Marie Jacquard]] develops his automated [[Jacquard loom]].<ref>{{Cite web |title=Programming patterns: the story of the Jacquard loom |url=https://www.scienceandindustrymuseum.org.uk/objects-and-stories/jacquard-loom |access-date=2023-04-12 |website=Science and Industry Museum |language=en}}</ref> * '''1804:''' [[Richard Trevithick]] invents the [[steam locomotive]].<ref>{{cite web |url=http://www.museumwales.ac.uk/en/rhagor/article/trevithic_loco/ |title=Richard Trevithick's steam locomotive | Rhagor |access-date=3 November 2009 |url-status=dead |archive-url=https://web.archive.org/web/20110415125004/http://www.museumwales.ac.uk/en/rhagor/article/trevithic_loco |archive-date=15 April 2011}}</ref> * '''1804:''' [[Hanaoka Seishū]] creates tsūsensan, the first modern [[general anesthetic]].<ref>{{cite journal|last1=Izuo|first1=M|title=Medical history: Seishu Hanaoka and his success in breast cancer surgery under general anesthesia two hundred years ago.|journal=Breast Cancer|date=2004|volume=11|issue=4|pages=319–324|pmid=15604985|location=Tokyo, Japan|doi=10.1007/bf02968037|s2cid=43428862}}</ref> * '''1807:''' [[Nicéphore Niépce]] invents an early [[internal combustion engine]] capable of doing useful work. * '''1807:''' [[François Isaac de Rivaz]] designs the first automobile powered by an [[internal combustion engine]] fuelled by [[hydrogen]]. * '''1807:''' [[Robert Fulton]] expands water transportation and trade with the workable steamboat.
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