Editing Epilepsy (section)

=== Animal models ===
[[Animal models of epilepsy|Animal models]] play a central role in epilepsy research, providing insight into seizure mechanisms, disease progression, and treatment effects. Rodents are most commonly used, with models based on chemical induction (e.g. kainic acid, pilocarpine), electrical stimulation (e.g. [[Kindling model of epilepsy|kindling]]), genetic mutations, and others.<ref>Guillemain, I., Kahane, P. & Depaulis, A. Animal models to study aetiopathology of epilepsy: what are the features to model? Epileptic Disord 14, 217–225 (2012).</ref> Other species, including [[zebrafish]], [[Dog|dogs]], and non-human primates, are also employed to capture features not easily replicated in rodents, such as complex behaviors or chronic seizure patterns. These models help researchers study epileptogenesis, test antiseizure drugs, and explore surgical or neuromodulatory interventions. While no model captures the full complexity of human epilepsy, they remain essential for translational research.<ref>{{Cite journal |last=Grone |first=Brian P |last2=Baraban |first2=Scott C |date=2015 |title=Animal models in epilepsy research: legacies and new directions |url=https://www.nature.com/articles/nn.3934 |journal=Nature Neuroscience |language=en |volume=18 |issue=3 |pages=339–343 |doi=10.1038/nn.3934 |issn=1097-6256}}</ref>