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===Individuals=== *[[Jamie Brewer]] is an American actress and model. She is best known for her roles in the [[FX (TV channel)|FX]] horror anthology television series ''[[American Horror Story]]''.<ref>{{Cite news | vauthors = Lawton A |date=2011-11-21 |title=Interview with Jamie Brewer |url=https://mediamikes.com/2011/11/interview-with-jamie-brewer/ |access-date=2023-04-01 |website=MediaMikes |language=en-US}}</ref> In its first season, ''[[American Horror Story: Murder House|Murder House]]'', she portrayed [[Adelaide Langdon|Adelaide "Addie" Langdon]]; in the third season, ''[[American Horror Story: Coven|Coven]]'', she portrayed [[Nan (American Horror Story)|Nan]], an enigmatic and [[clairvoyant]] [[witch]]; in the fourth season ''[[American Horror Story: Freak Show|Freak Show]]'', she portrayed Chester Creb's vision of his doll, Marjorie; in the seventh season ''[[American Horror Story: Cult|Cult]]'', she portrayed Hedda, a member of the 'SCUM' crew, led by feminist [[Valerie Solanas]]; and she also returned to her role as Nan in the eighth season, ''[[American Horror Story: Apocalypse|Apocalypse]]''. In February 2015, Brewer became the first woman with Down syndrome to walk the red carpet at [[New York Fashion Week]], for designer Carrie Hammer.<ref>{{Cite web | vauthors = Probus S, McNeal J |title=Meet The First Woman With Down Syndrome To Walk At Fashion Week |url=https://www.buzzfeednews.com/article/stephaniemcneal/meet-the-first-woman-with-down-syndrome-to-walk-at-fashion-w |access-date=2023-04-01 |website=BuzzFeed News |date=12 February 2015 |language=en}}</ref> *[[Sofía Jirau]] is a [[Puerto Ricans|Puerto Rican]] model with Down syndrome, working with designers and media outlets such as Vogue Mexico, People, and Hola!.<ref>{{Cite web |date=2020-02-19 |title=Puerto Rican model with Down Syndrome, Sofía Jirau is conquering the fashion world |url=https://www.hola.com/us/fashion/20211021325691/puerto-rican-model-down-syndrome-sofia-jirau/ |access-date=2023-04-01 |website=HOLA |language=en-US}}</ref><ref>{{Cite web | vauthors = Mier T | date = 17 February 2020 |title=NYFW: Model with Down Syndrome Says 'There Are No Limits' |url=https://people.com/human-interest/latina-model-with-down-syndrome-stuns-at-nyfw/ |access-date=2023-04-01 |website=Peoplemag |language=en}}</ref><ref>{{Cite web |date=2020-02-13 |title=Sofía Jirau, la modelo latina con síndrome de down que decantó en el Fashion Week de Nueva York |url=https://www.vogue.mx/moda/articulo/sofia-jirau-la-modelo-puertorriquena-con-sindrome-de-down-en-el-fashion-week-de-nueva-york |access-date=2023-04-01 |website=Vogue |language=es-MX}}</ref> In February 2020, Jirau made her debut at [[New York Fashion Week]].<ref>{{Cite web |last=V |first=Juliette |title=Latina Model With Down Syndrome Walks at New York Fashion Week |url=https://themighty.com/topic/down-syndrome/sofia-jirau-down-syndrome-model-new-york-fashion-week/ |access-date=2023-04-01 |website=The Mighty |language=en}}</ref> Then in February 2022, she became the first-ever model with Down Syndrome to be hired by the American retail company [[Victoria's Secret]].<ref>{{Cite web | vauthors = Holender S |date=2022-02-17 |title=Meet Sofia Jirau, Victoria's Secret's 1st Model With Down Syndrome |url=https://www.usmagazine.com/stylish/news/sofia-jirau-is-victorias-secrets-1st-model-with-down-syndrome/ |access-date=2023-04-01 |website=Us Weekly |language=en-US}}</ref> She walked the [[Los Angeles Fashion Week|LA Fashion Week]] runway in 2022.<ref name="About me">{{Cite web |title=About me |url=https://www.sofiajirau.com/en/quien-soy |access-date=2023-04-01 |website=Sofia Jirau Model |language=en}}</ref> Jirau launched a campaign in 2021 called Sin Límites or No Limits "which seeks to make visible the challenges facing the Down syndrome community, demonstrate our ability to achieve our goals, and raise awareness about the condition throughout the world."<ref name="About me" /> *[[Chris Nikic]] is the first person with Down syndrome to finish an [[Ironman Triathlon]].<ref>{{Cite news |title=Nikic becomes first person with Down's syndrome to finish Ironman |language=en-GB |work=BBC Sport |url=https://www.bbc.com/sport/triathlon/54869998 |access-date=2023-04-01}}</ref> He was awarded the [[Jimmy V Award|Jimmy V Award for Perseverance]] at the [[2021 ESPY Awards]].<ref>{{Cite web |date=2021-07-10 |title=2021 ESPYS award winners |url=https://www.espn.com/espys/story/_/page/voting-winners/2021-espys-award-winners |access-date=2023-04-01 |website=ESPN.com |language=en}}</ref> Nikic continues to run races around the world, using his platform to promote his 1% Better message and bring awareness to the endless possibilities for people with Down syndrome.<ref>{{Cite web |title=About – Chris Nikic |url=https://chrisnikic.com/about/ |access-date=2023-04-01 |language=en-US | work = chrisnikic.com }}</ref> *[[Grace Strobel]] is an American model and the first person with Down Syndrome to represent an American skin-care brand.<ref>{{Cite web | vauthors = Abelman D | date = 21 March 2021 |title=Grace Strobel Knows How Good Her Skin Looks |url=https://www.allure.com/story/grace-strobel-obagi-skin-care-routine-interview |access-date=2023-04-01 |website=Allure |language=en-US}}</ref> She first joined Obagi in 2020, and continues to be an Ambassador for the brand as of 2022.<ref>{{Cite press release |last=Obagi |title=Obagi Announces Partnership with Down Syndrome Advocate, Grace Strobel, as new SKINCLUSION Ambassador and Face of New Obagi Clinical Cleanser |url=https://www.prnewswire.com/news-releases/obagi-announces-partnership-with-down-syndrome-advocate-grace-strobel-as-new-skinclusion-ambassador-and-face-of-new-obagi-clinical-cleanser-301143570.html |access-date=2023-04-01 |website=www.prnewswire.com |language=en}}</ref><ref>{{Cite press release |last=Obagi |title=Obagi Clinical® Continues Collaboration with Down Syndrome Advocate Grace Strobel |url=https://www.prnewswire.com/news-releases/obagi-clinical-continues-collaboration-with-down-syndrome-advocate-grace-strobel-301532656.html |access-date=2023-04-01 |website=www.prnewswire.com |language=en}}</ref> She walked the runway representing [[Tommy Hilfiger (company)|Tommy Hilfiger]] for Runway of Dreams [[New York Fashion Week]] 2020 and [[Atlantic City Fashion Week]].<ref name="At just 25 years old, Chesterfield native Grace Strobel continues to shatter stereotypes, shift societal expectations and make history.">{{Cite web | vauthors = LeBlanc DA |title=The Grace Effect: Local model is on a mission to change the world in style |url=https://www.westnewsmagazine.com/lifestyles/the-grace-effect-local-model-is-on-a-mission-to-change-the-world-in-style/article_af990822-99d2-11ec-a659-6fef10246f05.html |access-date=2023-04-01 |website=WestNewsMagazine.com |date=March 2022 |language=en}}</ref> Strobel has been featured in ''[[Forbes]]'', on [[Today (American TV program)|''The Today Show'']], ''[[Good Morning America]]'', by [[Rihanna]]'s [[Fenty Beauty]], Lady Gaga's Kindness Channel, and many more.<ref name="At just 25 years old, Chesterfield native Grace Strobel continues to shatter stereotypes, shift societal expectations and make history." /><ref name="The Grace Effect" /> She is also a public speaker and gives a presentation called #TheGraceEffect about what it is like to live with Down syndrome.<ref>{{Cite web |title=Down syndrome advocate Grace Strobel on pushing boundaries: 'Let no one tell you what you can and cannot achieve' |url=https://www.yahoo.com/lifestyle/down-syndrome-advocate-grace-strobel-on-pushing-boundaries-201717691.html |access-date=2023-04-01 |website=Yahoo Life |date=21 March 2022 |language=en-US}}</ref><ref name="The Grace Effect">{{Cite web | vauthors = Strobel G |date=2020-01-24 |title=#TheGraceEffect – Creating Ripples With Kindness And Respect |url=https://www.channelkindness.org/the-grace-effect/ |access-date=2023-04-01 |website=Channel Kindness |language=en-US}}</ref>
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