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===Malaria=== Malaria and vitamin A deficiency are both common among young children in sub-Saharan Africa. Vitamin A supplementation to children in regions where vitamin A deficiency is common has repeatedly been shown to reduce overall mortality rates, especially from measles and diarrhea.<ref name="Sanj2009"/> For malaria, clinical trial results are mixed, either showing that vitamin A treatment did not reduce the incidence of probable malarial fever, or else did not affect incidence, but did reduce slide-confirmed parasite density and reduced the number of fever episodes.<ref name="Sanj2009">{{cite journal | vauthors = Sanjoaquin MA, Molyneux ME | title = Malaria and vitamin A deficiency in African children: a vicious circle? | journal = Malaria Journal | volume = 8 | pages = 134 | date = June 2009 | pmid = 19534807 | pmc = 2702350 | doi = 10.1186/1475-2875-8-134 | doi-access = free | title-link = doi }}</ref> The question was raised as to whether malaria causes vitamin A deficiency, or vitamin A deficiency contributes to the severity of malaria, or both. Researchers proposed several mechanisms by which malaria (and other infections) could contribute to vitamin A deficiency, including a fever-induced reduction in synthesis of retinal-binding protein (RBP) responsible for transporting retinol from liver to plasma and tissues, but reported finding no evidence for a transient depression or restoration of plasma RBP or retinol after a malarial infection was eliminated.<ref name="Sanj2009"/>
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