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==== Intoxication ==== {{Main|Alcohol enema}} Noting that deaths have been reported from [[alcohol poisoning]] via enemas,<ref>{{cite web |url = http://darwinawards.com/darwin/darwin2007-13.html |title = The Enema Within |access-date = 11 January 2008 |year = 2008 |publisher = [[Darwin Awards]] }}</ref> an [[alcohol enema]] can be used to very quickly instill alcohol into the bloodstream, absorbed through the membranes of the colon. However, great care must be taken as to the amount of alcohol used. Only a small amount is needed as the intestine absorbs the alcohol far more quickly than the stomach. When enema is prescribed for the administration of drugs or alcohol, a cleansing enema may first be used to clean the colon to help increase the rate of absorption.<ref name="pmid6126289">{{cite journal |vauthors = de Boer AG, Moolenaar F, de Leede LG, Breimer DD |title = Rectal drug administration: clinical pharmacokinetic considerations |journal = Clin Pharmacokinet |volume = 7 |issue = 4 |pages = 285β311 |year = 1982 |pmid = 6126289 |doi = 10.2165/00003088-198207040-00002 |s2cid = 41562861 }}</ref>
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