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Sjögren's disease
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===Burden of illness=== Sjögren's disease is associated with a high burden of illness,<ref>{{cite journal |last1=Vivino |first1=Frederick B. |title=Sjogren's syndrome: Clinical aspects |journal=Clinical Immunology |date=September 2017 |volume=182 |pages=48–54 |doi=10.1016/j.clim.2017.04.005 |pmid=28428095 }}</ref> and has been shown to markedly reduce [[HRQoL|quality of life]] (QoL),<ref>{{cite web | url=https://www.sjogrens.org/understanding-sjogrens/resources/patient-survey-results | title=Patient Survey Results }}</ref> with a significant impact on ability to work resulting from increased rates of disability.<ref>{{cite journal |last1=Meijer |first1=Jiska M. |last2=Meiners |first2=Petra M. |last3=Huddleston Slater |first3=James J. R. |last4=Spijkervet |first4=Fred K. L. |last5=Kallenberg |first5=Cees G. M. |last6=Vissink |first6=Arjan |last7=Bootsma |first7=Hendrika |title=Health-related quality of life, employment and disability in patients with Sjögren's disease |journal=Rheumatology |date=September 2009 |volume=48 |issue=9 |pages=1077–1082 |doi=10.1093/rheumatology/kep141 |pmid=19553376 }}</ref><ref name=":0">{{cite journal |last1=Miyamoto |first1=Samira T |last2=Valim |first2=Valéria |last3=Fisher |first3=Benjamin A |title=Health-related quality of life and costs in Sjögren's syndrome |journal=Rheumatology |date=18 June 2021 |volume=60 |issue=6 |pages=2588–2601 |doi=10.1093/rheumatology/key370 |pmid=30770918 |url=http://pure-oai.bham.ac.uk/ws/files/54982264/HRQoL_and_cost_revised_v2_final_clean_with_figures.pdf }}</ref><ref>{{cite journal |last1=Zhang |first1=Qiuxiang |last2=Wang |first2=Xulin |last3=Chen |first3=Haoyang |last4=Shen |first4=Biyu |title=Sjögren's syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from Short Form 36 questionnaire and a meta-analysis |journal=Patient Preference and Adherence |date=10 May 2017 |volume=11 |pages=905–911 |doi=10.2147/PPA.S132751 |pmid=28546741 |pmc=5436777 |doi-access=free }}</ref> The reduction in QoL is similar to that seen in other chronic conditions such as [[rheumatoid arthritis]], [[lupus]] and [[fibromyalgia]].<ref name=":0" />
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