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=== Endoscopy === A [[colonoscopy]] is the best test for making the diagnosis of Crohn's disease, as it allows direct visualization of the colon and the [[terminal ileum]], identifying the pattern of disease involvement. On occasion, the colonoscope can travel past the terminal ileum, but it varies from person to person. During the procedure, the [[gastroenterologist]] can also perform a biopsy, taking small samples of tissue for laboratory analysis, which may help confirm a diagnosis. As 30% of Crohn's disease involves only the ileum,<ref name="Baumgart2012" /> [[cannula]]tion of the terminal ileum is required in making the diagnosis. Finding a patchy distribution of disease, with involvement of the colon or ileum, but not the [[rectum]], is suggestive of Crohn's disease, as are other endoscopic stigmata.<ref name="Hara2006" /> The utility of capsule endoscopy for this, however, is still uncertain.<ref>{{cite journal | vauthors = Triester SL, Leighton JA, Leontiadis GI, Gurudu SR, Fleischer DE, Hara AK, Heigh RI, Shiff AD, Sharma VK | title = A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in people with non-stricturing small bowel Crohn's disease | journal = The American Journal of Gastroenterology | volume = 101 | issue = 5 | pages = 954β964 | date = May 2006 | pmid = 16696781 | doi = 10.1111/j.1572-0241.2006.00506.x | s2cid = 25684863 }}</ref>
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