Editing Vitamin B6 (section)

===Biosynthesis===
{{Main|Pyridoxal phosphate #Biosynthesis}}

Two pathways for PLP are currently known: one requires deoxyxylulose 5-phosphate (DXP), while the other does not, hence they are known as DXP-dependent and DXP-independent. These pathways have been studied extensively in ''[[Escherichia coli]]''<ref>{{cite journal |vauthors=Tambasco-Studart M, Titiz O, Raschle T, Forster G, Amrhein N, Fitzpatrick TB |title=Vitamin B<sub>6</sub> biosynthesis in higher plants |journal=Proc Natl Acad Sci U S A |volume=102 |issue=38 |pages=13687–92 |date=September 2005 |pmid=16157873 |pmc=1224648 |doi=10.1073/pnas.0506228102 |bibcode=2005PNAS..10213687T |url=|doi-access=free }}</ref> and ''[[Bacillus subtilis]]'', respectively. Despite the disparity in the starting compounds and the different number of steps required, the two pathways possess many commonalities.<ref>{{cite journal | vauthors = Fitzpatrick TB, Amrhein N, Kappes B, Macheroux P, Tews I, Raschle T | title = Two independent routes of de novo vitamin B<sub>6</sub> biosynthesis: not that different after all | journal = The Biochemical Journal | volume = 407 | issue = 1 | pages = 1–13 | date = October 2007 | pmid = 17822383 | pmc =2267407 | doi = 10.1042/BJ20070765 | s2cid = 28231094 }}</ref> The DXP-dependent pathway:
[[File:Metabolic pathway- pyridoxal 5'-phosphate biosynthesis I v 2.0.svg|700px|center|class=skin-invert-image]]