Editing Striatum (section)

====Matrix and striosomes====
[[Neurochemistry]] studies have used [[staining|staining techniques]] on the striatum that have identified two distinct striatal compartments, the matrix, and the [[striosome]] (or patch). The matrix is seen to be rich in [[acetylcholinesterase]], while the embedded striosomes are acetylcholinesterase-poor.<ref name="Brimblecombe"/> The matrix forms the bulk of the striatum, and receives input from most areas of the cerebral cortex.<ref name="Squire">{{cite book |last1=Squire |first1=Larry |title=Fundamental neuroscience |date=2013 |publisher=Elsevier Academic Press |location=Amsterdam Heidelberg |isbn=9780123858702 |page=658 |edition=4.}}</ref> Clusters of neurons in the matrix, called matrisomes receive a similar input. Their output goes to both regions of the globus pallidus and to the substantia nigra pars reticulata.<ref name="Squire"/>

The striosomes receive input from the prefrontal cortex and give outputs to the substantia nigra pars compacta.<ref name="Squire"/> There are more striosomes present in the dorsal striatum making up 10-15% of the striatal volume, than in the ventral striatum.<ref name="Brimblecombe">{{Cite journal|pmid=27977131|year=2017|last1=Brimblecombe|first1=K. R.|title=The Striosome and Matrix Compartments of the Striatum: A Path through the Labyrinth from Neurochemistry toward Function|journal=ACS Chemical Neuroscience|volume=8|issue=2|pages=235–242|last2=Cragg|first2=S. J.|doi=10.1021/acschemneuro.6b00333|doi-access=free}}</ref>