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==Health== [[File:Shiba inu taiki.jpg|thumb|A Shiba Inu in Italy, 2008]] A study in Japan on [[patella luxation]] in small breeds found the Shiba Inu to have the second highest rate of the condition, with 35% of the Shiba Inus surveyed being affected.<ref>{{cite journal | last1=Maeda | first1=Kazuhiro | last2=Inoue | first2=Mai | last3= Tanaka | first3=Miho | last4=Momozawa | first4=Yukihide | title=Evidence of genetic contribution to patellar luxation in Toy Poodle puppies | journal=Journal of Veterinary Medical Science | publisher= Japanese Society of Veterinary Science | volume=81 | issue=4 | year=2019 | issn=0916-7250 | doi=10.1292/jvms.18-0485 | pages=532β537| pmid= 30745525 | pmc=6483903 }}</ref> Three genes belonging to the breed were associated with [[glaucoma]] were found in an analysis of [[DNA sequencing]].<ref>{{cite journal | last1=Kanemaki | first1=Nobuyuki | last2=Tchedre | first2=Kissaou T. | last3=Imayasu | first3=Masaki | last4=Kawarai | first4=Shinpei | last5= Sakaguchi | first5=Masahiro | last6=Yoshino | first6=Atsushi | last7=Itoh | first7=Norihiko | last8=Meguro | first8=Akira | last9=Mizuki | first9= Nobuhisa | display-authors= 3| title=Dogs and Humans Share a Common Susceptibility Gene SRBD1 for Glaucoma Risk | journal=PLOS ONE | publisher=Public Library of Science (PLoS) | volume=8 | issue=9 | date=2013-09-11 | issn=1932-6203 | doi=10.1371/journal.pone.0074372 | doi-access=free | page=e74372| pmid= 24040232 | pmc=3770690 | bibcode=2013PLoSO...874372K }}</ref> Another study from Japan reviewing cases of dogs presented for [[ophthalmologic]] examination found the Shiba Inu to make up 33% of all glaucoma cases whilst only making up 2.7% of the total population used in the study.<ref>{{cite journal | last1=Kato | first1=Kumiko | last2=Sasaki | first2=Nobuo | last3=Matsunaga | first3=Satoru | last4=Nishimura | first4=Ryohei | last5= Ogawa | first5= Hiroyuki | display-authors= 3 | title=Incidence of Canine Glaucoma with Goniodysplasia in Japan: A Retrospective Study | journal=Journal of Veterinary Medical Science | publisher=Japanese Society of Veterinary Science | volume=68 | issue=8 | year=2006 | issn=0916-7250 | doi=10.1292/jvms.68.853 | pages= 853β858| doi-access=free | pmid=16953087 }}</ref> [[Pyometra]], a uterine infection of intact bitches, is slightly more common in the Shiba Inu.<ref>{{cite web |title=Shiba Inu |url=https://ahcfargo.com/client-resources/breed-info/shiba-inu/ |website= ahcfargo.com| publisher= Animal Health Clinic, Fargo |access-date=26 January 2024 |archive-date=26 January 2024 |archive-url=https://web.archive.org/web/20240126230614/https://ahcfargo.com/client-resources/breed-info/shiba-inu/ |url-status=dead }}</ref><ref>{{cite web |title=Shiba Inu |url=https://jollyrdveterinaryhospital.com/client-resources/breed-info/shiba-inu/ |website= jollyrdveterinaryhospital.com| publisher= Jolly Road Veterinary Hospital |access-date=26 January 2024}}</ref> The Shiba Inu is predisposed to [[Dog skin disorders|canine atopic dermatitis]].<ref>{{cite journal | last1=Tanaka | first1=Kazuaki | last2=Yamamoto-Fukuda | first2=Misaki | last3=Tazikawa | first3= Tatsuya | last4=Shimakura | first4=Hidekatsu | last5= Sakaguchi | first5=Masahiro | display-authors= 3| title=Association analysis of non-synonymous polymorphisms of interleukin-4 receptor-Ξ± and interleukin-13 genes in canine atopic dermatitis | journal=Journal of Veterinary Medical Science | publisher= Japanese Society of Veterinary Science | volume= 82 | issue=9 | year=2020 | issn=0916-7250 | doi=10.1292/jvms.20-0301 | pages=1253β1259| pmid= 32669513 | pmc=7538314 }}</ref><ref>{{cite journal | last1= Fujimura | first1=M. | last2=Ishimaru | first2=H. | last3=Nakatsuji | first3=Y. | title= Fluoxetine (SSRI) treatment of canine atopic dermatitis: a randomized, double-blind, placebo-controlled, crossover trial | journal=Polish Journal of Veterinary Sciences | publisher=Polish Academy of Sciences Chancellery | volume=17 | issue=2 | date=2014-06-01 | issn=2300-2557 | doi=10.2478/pjvs-2014-0053 | pages=371β373| pmid=24988868 }}</ref><ref>{{cite journal | last1=Wood | first1=Shona Hiedi | last2=Ke | first2=Xiayi | last3=Nuttall | first3=Tim | last4=McEwan | first4=Neil | last5=Ollier | first5= William E. | last6=Carter | first6=Stuart D. | display-authors= 3| title=Genome-wide association analysis of canine atopic dermatitis and identification of disease related SNPs | journal=Immunogenetics | publisher=Springer Science and Business Media LLC | volume=61 | issue=11β12 | year=2009 | issn= 0093-7711 | doi=10.1007/s00251-009-0402-y | pages=765β772| pmid=19838693 }}</ref> An auto-immune disease common in Akitas [[Vogt-Koyanagi-Harada-like syndrome]] is known to occur in the Shiba Inu.<ref>{{cite web |title=The detail information of Vogt-Koyanagi-Harada-like syndrome |url = https://ngdc.cncb.ac.cn/idog/disease/getDiseaseDetailById.action?diseaseId=329 |website= ngdc.cncb.ac.cn| publisher= National Genomics Data Center, China National Center for Bioinformation |access-date=26 January 2024 |archive-date=26 January 2024 |archive-url= https://web.archive.org/web/20240126230612/https://ngdc.cncb.ac.cn/idog/disease/getDiseaseDetailById.action?diseaseId=329 |url-status=dead }}</ref> ===Lifespan=== A review of cemetery data in Japan found that the Shiba Inu had a life expectancy of 15.5 years,<ref>{{cite journal |last1= Inoue |first1=Mai |last2=C. L. Kwan |first2=Nigel |last3=Sugiura |first3=Katsuaki |date= 2018 |title=Estimating the life expectancy of companion dogs in Japan using pet cemetery data |journal=J Vet Med Sci |volume=80| number= 7 |pages=1153β1158 |doi= 10.1292/jvms.17-0384 |pmc=6068313 |pmid= 29798968}}</ref> greater than any other breed. A 2024 UK study found a life expectancy of 14.6 years for the breed compared to an average of 12.7 for purebreeds and 12 for [[Mongrel|crossbreeds]].<ref>{{cite journal | last1=McMillan | first1=Kirsten M. | last2=Bielby | first2=Jon | last3=Williams | first3= Carys L. | last4= Upjohn | first4=Melissa M. | last5=Casey | first5=Rachel A. | last6=Christley | first6=Robert M. | display-authors= 3| title= Longevity of companion dog breeds: those at risk from early death | journal=Scientific Reports | publisher=Springer Science and Business Media LLC | volume= 14 | number=1 | date=2024-02-01 | issn=2045-2322 | doi=10.1038/s41598-023-50458-w | page=531| pmid=38302530 | pmc=10834484 | bibcode= 2024NatSR..14..531M }}</ref>
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