Editing Serotonin syndrome (section)

===Spectrum concept===
A postulated "spectrum concept" of serotonin toxicity emphasises the role that progressively increasing serotonin levels play in mediating the clinical picture as side effects merge into toxicity. The [[dose-response relationship]] is the effect of progressive elevation of serotonin, either by raising the dose of one drug, or combining it with another serotonergic drug which may produce large elevations in serotonin levels.<ref>{{cite journal|author=Gillman PK |title=The spectrum concept of serotonin toxicity |journal=Pain Med |volume=5 |issue=2 |pages=231–2 |date=June 2004 |pmid=15209988 |doi=10.1111/j.1526-4637.2004.04033.x|doi-access= }}</ref><ref name="Gillman PK-2006" /> Some experts prefer the terms serotonin toxicity or serotonin toxidrome, to more accurately reflect that it is a form of [[poisoning]].<ref name="Isbister Buckley"/><ref name="Gillman PK-2006">{{cite journal|author=Gillman PK |title=A review of serotonin toxicity data: implications for the mechanisms of antidepressant drug action |journal=Biol Psychiatry |volume=59 |issue=11 |pages=1046–51 |date=June 2006 |pmid=16460699 |doi=10.1016/j.biopsych.2005.11.016 |s2cid=12179122 }}</ref>