Editing Riboflavin (section)

===Micronutrient metabolism===
Riboflavin, FMN, and FAD are involved in the metabolism of niacin, vitamin B<sub>6</sub>, and [[folate]].<ref name="DRItext" /> The synthesis of the niacin-containing coenzymes, [[Nicotinamide adenine dinucleotide|NAD]] and [[Nicotinamide adenine dinucleotide phosphate|NADP]], from tryptophan involves the FAD-dependent enzyme, [[kynurenine 3-monooxygenase]]. Dietary deficiency of riboflavin can decrease the production of NAD and NADP, thereby promoting niacin deficiency.<ref name="DRItext" /> Conversion of vitamin B<sub>6</sub> to its coenzyme, [[pyridoxal 5'-phosphate]], involves the enzyme, [[pyridoxine 5'-phosphate oxidase]], which requires FMN.<ref name="DRItext" /> An enzyme involved in folate metabolism, [[5,10-methylenetetrahydrofolate]] [[reductase]], requires FAD to form the amino acid, [[methionine]], from homocysteine.<ref name="DRItext" />

Riboflavin deficiency appears to impair the metabolism of the [[Mineral (nutrient)|dietary mineral]], [[iron]], which is essential to the production of [[hemoglobin]] and [[red blood cell]]s. Alleviating riboflavin deficiency in people who are deficient in both riboflavin and iron improves the effectiveness of [[iron supplement]]ation for treating [[iron-deficiency anemia]].<ref>{{cite journal |vauthors=Fishman SM, Christian P, West KP |title=The role of vitamins in the prevention and control of anaemia |journal=Public Health Nutr |volume=3 |issue=2 |pages=125–50 |date=June 2000 |pmid=10948381 |doi=10.1017/s1368980000000173 |url=|doi-access=free }}</ref>