Editing Oxycodone (section)

===Dependence and withdrawal===
{{See also|Opioid dependence}}
[[File:OxyContin setup.jpg|thumb|OxyContin tablets crushed into powder for insufflation (snorting). Notice the tablets at the top with the coating removed]]

The risk of experiencing severe [[Drug withdrawal|withdrawal]] symptoms is high if a patient has become physically dependent and discontinues oxycodone abruptly. Medically, when the drug has been taken regularly over an extended period, it is withdrawn gradually rather than abruptly. People who regularly use oxycodone recreationally or at higher than prescribed doses are at even higher risk of severe withdrawal symptoms. The symptoms of oxycodone withdrawal, as with other opioids, may include "[[anxiety]], [[panic attack]], [[nausea]], [[insomnia]], [[muscle pain]], [[muscle weakness]], [[fever]]s, and other [[flu-like syndrome|flu-like symptoms]]".<ref name="CESAR2005">{{cite web |url=http://www.cesar.umd.edu/cesar/drugs/oxycodone.asp |title=Oxycodone |access-date=25 March 2009 |date=2 May 2005 |publisher=Center for Substance Abuse Research |archive-date=6 April 2009 |archive-url=https://web.archive.org/web/20090406010900/http://www.cesar.umd.edu/cesar/drugs/oxycodone.asp |url-status=dead }}</ref><ref>{{cite web|title=Tapering off opioids: When and how|publisher=Mayo Clinic|url=https://www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/in-depth/tapering-off-opioids-when-and-how/art-20386036|access-date=10 October 2020}}</ref>

Withdrawal symptoms have also been reported in newborns whose mothers had been either injecting or orally taking oxycodone during pregnancy.<ref>{{cite journal | vauthors = Rao R, Desai NS | title = OxyContin and neonatal abstinence syndrome | journal = Journal of Perinatology | volume = 22 | issue = 4 | pages = 324–325 | date = June 2002 | pmid = 12032797 | doi = 10.1038/sj.jp.7210744 | s2cid = 22539877  }}</ref>